China Factory Direct
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| CAS number | 29848-57-5 |
| Product name | 1-(Difluoromethyl)-4-nitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor drugs | Reduction of nitro groups to prepare amines |
| Agrochemicals | Intermediate for herbicide production | Grignard reaction or substitution reaction to introduce specific functional groups |
| Dyes | Intermediate for synthesizing acid dyes | Sulfonation to prepare dye precursors containing sulfonic acid groups |
| Organic Synthesis | Used to synthesize fluorinated aromatic compounds | Nucleophilic substitution to introduce a difluoromethyl group |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under validated chromatographic conditions. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile solvents are equilibrated in headspace vial and quantified by GC-FID using calibrated standard solutions. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Sample digested in acid matrix; elemental emission intensities measured at characteristic wavelengths for quantitative metal analysis. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on ion-exchange column followed by conductivity-based quantification relative to chloride standards. |
| Nitro Group Content | UV-Vis Spectrophotometry | Quantification of nitrobenzene derivative via absorbance measurement at characteristic wavelength (e.g., ~265 nm) in suitable solvent. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution with phenolphthalein endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually as solid-to-liquid phase change under controlled heating rate per pharmacopeial guidelines. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified criteria (e.g., white to pale yellow crystalline solid, free from visible particles). |
| Loss on Drying (LOD) | Gravimetric Analysis (Thermogravimetry) | Mass loss measured after drying under specified temperature and vacuum/time conditions, reported as weight percent. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using reverse-phase column and UV detection at appropriate wavelength. |
| Residue on Ignition | Sulfated Ash Gravimetry | Sample ignited after sulfuric acid treatment; residual inorganic ash weighed following high-temperature incineration. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Melting Point | -15 to -10 °C |
| Refractive Index (n20/D) | 1.530–1.540 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.