S-Adenosyl-L-methionine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 29908-03-0 |
| Product name | S-Adenosyl-L-methionine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for S-Adenosyl-L-methionine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk S-Adenosyl-L-methionine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of S-Adenosyl-L-methionine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Active pharmaceutical ingredient (API) for antidepressant, hepatoprotective, and osteoarthritis treatments | Formulation: Synthesis and preparation for tablets, injectables, or oral solutions |
| Biotechnology | Methyl donor for enzymatic methylation reaction studies | Molecular biology assays: In vitro methylation of DNA, RNA, proteins, and small molecules |
| Food & Nutritional Supplements | Ingredient in dietary supplements supporting liver function and mood regulation | Microencapsulation or lyophilization: Enhances stability for capsule or tablet manufacturing |
| Chemical Synthesis | Chiral methylating reagent | Organic synthesis: Introduction of methyl groups in asymmetric reactions |
| Agricultural Biotechnology | Research tool for plant metabolic regulation | Laboratory use: Modulation of endogenous plant hormone levels and stress response studies |
Manufacturing Quality Control of S-Adenosyl-L-methionine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (SAM content) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison with reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., SAH, homocysteine, methionine) using gradient HPLC-UV against qualified reference standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water based on stoichiometric reaction with iodine and sulfur dioxide. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 C to combust organic matter; residue mass measured as inorganic ash content. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion using inductively coupled plasma mass spectrometry for ultra-trace metal detection. |
| pH (1% aqueous solution) | Potentiometric Titration | Measurement of hydrogen ion activity using calibrated pH electrode in a standardized aqueous solution. |
| Optical Rotation | [alpha]D | Measurement of specific rotation using sodium D-line light source in a polarimeter to confirm chiral purity and identity. |
| Microbial Contamination | Membrane Filtration | Filtration of solution followed by incubation on selective agar media to enumerate aerobic microorganisms and detect absence of specified pathogens. |
| Endotoxins | LAL Assay | Quantitative detection via Limulus amebocyte lysate gel-clot or kinetic chromogenic method measuring coagulation response to endotoxin. |
| Residual Solvents | GC-FID | Identification and quantification of volatile solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed powder using Mie scattering theory to determine volume-based particle size distribution. |
| Sterility | Direct Inoculation | Aseptic transfer of product into soybean-casein digest medium followed by incubation and visual assessment for microbial growth. |
Technical Specifications of S-Adenosyl-L-methionine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -27.0 to -31.0 deg (c=1, H2O) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of S-Adenosyl-L-methionine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of S-Adenosyl-L-methionine
Packaging of S-Adenosyl-L-methionine
Industrial S-Adenosyl-L-methionine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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