Tetrahydro-4H-pyran-4-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 29943-42-8 |
| Product name | Tetrahydro-4H-pyran-4-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Tetrahydro-4H-pyran-4-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Tetrahydro-4H-pyran-4-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Tetrahydro-4H-pyran-4-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antifungal drug terbinafine | Catalytic hydrogenation or reduction of 2-pyranone to tetrahydropyranone, followed by amination and alkylation to construct the terbinafine molecular scaffold |
| Agrochemicals | Structural building block for novel insecticides and plant growth regulators | Acts as a heterocyclic synthon in cycloaddition or nucleophilic substitution reactions to introduce an oxygen-containing saturated six-membered heterocycle, enhancing biological activity and metabolic stability |
| Fine Fragrances | Fixative component and precursor in fruity fragrance formulations | Ring-opening polymerization under acidic conditions or condensation with aldehydes to generate cyclic acetal derivatives exhibiting persistent sweet and green olfactory notes |
| Organic Synthesis | General chiral synthon and cyclic carbonyl reagent | Used in asymmetric reduction, enolization/alkylation, and Baeyer–Villiger oxidation to construct chiral γ-butyrolactone derivatives and multifunctional complex molecules |
Manufacturing Quality Control of Tetrahydro-4H-pyran-4-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies tetrahydropyranone by separation on a capillary column and flame ionization detection relative to a certified reference standard. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration using iodine generated electrochemically in a methanol-based reagent. |
| Acidity (as Acetic Acid) | Acid-Base Titration with NaOH | Determines acidic impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled high-temperature ashing and subsequent weighing. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Quantifies trace heavy metals by plasma ionization followed by mass spectrometric detection with isotopic resolution. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Color (APHA) | Visual Comparison or Spectrophotometry | Evaluates yellowness by matching sample color to APHA platinum-cobalt standards or measuring absorbance at 430 nm. |
| Refractive Index | Refractometry | Determines refractive index at 20 degrees C using a calibrated Abbe refractometer based on critical angle of total internal reflection. |
| Specific Gravity | Digital Density Meter | Measures density relative to water at 20 degrees C via oscillating U-tube principle with temperature-controlled sample cell. |
| Non-Volatile Residue | Evaporation and Gravimetry | Quantifies residual solids after evaporation of a fixed sample volume under controlled vacuum and temperature, followed by weighing. |
| Aldehyde Impurities | HPLC with UV Detection | Separates and detects aldehyde impurities using reversed-phase chromatography and UV absorbance at 210 nm. |
| Residual Solvents (e.g., THF, MeOH) | Headspace GC-FID | Quantifies volatile organic solvents by gas-phase equilibration followed by capillary GC separation and FID detection. |
Technical Specifications of Tetrahydro-4H-pyran-4-one
| Test Item | Specification |
|---|---|
| Appearance | Light yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.445–1.455 |
| Relative Density (20°C/25°C) | 0.970–0.990 g/cm³ |
| Odor | Characteristic mild odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Tetrahydro-4H-pyran-4-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Tetrahydro-4H-pyran-4-one
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Industrial Tetrahydro-4H-pyran-4-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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