DL-THYROXINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 300-30-1 |
| Product name | DL-THYROXINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for DL-THYROXINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk DL-THYROXINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of DL-THYROXINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in research on the mechanism of action and physiological functions of thyroid hormones | Prepared via chemical synthesis to produce DL-thyroxine |
| Biotechnology | Used as a reference standard or control substance | Purified and characterized using high-performance liquid chromatography (HPLC) |
Manufacturing Quality Control of DL-THYROXINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies DL-thyroxine content using reverse-phase HPLC with UV detection at 225 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., L-thyroxine, D-thyroxine, desiodo analogs) using gradient HPLC-UV with system suitability criteria. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection, per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Determines trace heavy metal impurities (Pb, Cd, As, Hg, Ni) via inductively coupled plasma mass spectrometry after acid digestion. |
| Water Content | Karl Fischer Titration | Quantifies water by volumetric or coulometric Karl Fischer titration, based on stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Specific Optical Rotation | Polarimetry | Measures optical activity using sodium D-line light to confirm chiral integrity and detect racemization extent. |
| pH of Aqueous Suspension | pH Meter | Determines pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode, indicating acidic/basic degradation products. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic residue after controlled high-temperature ashing, indicating non-volatile inorganic contaminants or catalyst residues. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersion using laser diffraction to determine D10, D50, D90 values relevant to dissolution and handling. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli, Salmonella) per USP <61> and <62>. |
| Loss on Drying | Thermogravimetry | Measures volatile loss (moisture + solvents) under controlled heating (e.g., 105 C, 2 h) using analytical balance and oven. |
| Identity Confirmation | FTIR Spectroscopy | Verifies molecular structure by comparing sample IR spectrum (KBr pellet) to reference standard spectrum using characteristic functional group absorptions. |
Technical Specifications of DL-THYROXINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 230-235°C (decomposes) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -2.5° to +2.5° (c=1 in 0.1N NaOH) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of DL-THYROXINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of DL-THYROXINE
Industrial DL-THYROXINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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