S-TERT-BUTYLMERCAPTO-L-CYSTEINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 30044-51-0 |
| Product name | S-TERT-BUTYLMERCAPTO-L-CYSTEINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for S-TERT-BUTYLMERCAPTO-L-CYSTEINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk S-TERT-BUTYLMERCAPTO-L-CYSTEINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of S-TERT-BUTYLMERCAPTO-L-CYSTEINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral cysteine derivative protecting agent in peptide drug synthesis | Selectively protects the thiol group of cysteine residues during solid-phase peptide synthesis (SPPS) to prevent oxidation and side reactions; the tert-butylthio protecting group is subsequently removed with trifluoroacetic acid (TFA) |
| Biochemical Research | Site-specific cysteine modification reagent for protein structure and function studies | Enables site-specific thiol protection and controlled release in vitro for protein labeling or crosslinking experiments, supporting analysis of disulfide bond formation mechanisms and conformational dynamics |
| Organic Synthesis | Building block for chiral thioether compounds | Acts as a chiral auxiliary in asymmetric alkylation and cyclization reactions to synthesize sulfur-containing chiral pharmaceutical intermediates (e.g., precursors to protease inhibitors) |
Manufacturing Quality Control of S-TERT-BUTYLMERCAPTO-L-CYSTEINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 205–220 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment via separation on a chiral stationary phase (e.g., cellulose-based column) with UV detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, ethyl acetate) using capillary GC with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, leveraging high sensitivity and isotopic resolution. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Optical Rotation | [α]D Measurement | Determination of specific rotation using a polarimeter at 20 °C and sodium D-line (589 nm), indicating chiral integrity and concentration. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in aqueous suspension to assess acid-base character and degradation potential. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detection and quantification of structurally related impurities (e.g., disulfide dimer, dealkylated analogs) under stressed conditions (acid/base/oxidative/thermal). |
| Microbial Contamination | Membrane Filtration & Plate Count | Enumeration of aerobic mesophilic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial limits. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using light scattering principles to ensure consistent handling and dissolution behavior. |
| Sulfur Content | Combustion IC | Quantitative determination of total sulfur by high-temperature combustion followed by ion chromatographic detection of sulfate ions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition analysis to verify identity and crystallinity; deviation indicates polymorphic change or impurity presence. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Weight loss measurement upon controlled heating (e.g., 105 °C, 2 h) to determine volatile content excluding water (complementary to KF). |
Technical Specifications of S-TERT-BUTYLMERCAPTO-L-CYSTEINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 162-166°C |
| Optical Rotation | +18.0° to +22.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of S-TERT-BUTYLMERCAPTO-L-CYSTEINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of S-TERT-BUTYLMERCAPTO-L-CYSTEINE
Industrial S-TERT-BUTYLMERCAPTO-L-CYSTEINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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