China Factory Direct
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| CAS number | 3014-80-0 |
| Product name | H-VAL-NH2 HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antiviral drugs (e.g., valganciclovir) | Prepared from L-valine via amidation, salt formation, and other steps for subsequent drug molecule construction |
| Chemical Synthesis | Chiral building block for peptide and peptidomimetic compound synthesis | Used as a protected amino acid derivative in solid-phase or solution-phase peptide synthesis to participate in coupling reactions |
| Biopharmaceutical R&D | Research tool for enzyme inhibitors or receptor ligands | Integrated as a structural unit into target molecules to study interactions with biological targets |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (L-Valinamide HCl content) | Acid-base titration with NaOH | Quantitative neutralization of HCl salt using standardized sodium hydroxide solution, with potentiometric or indicator endpoint detection. |
| Chiral Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, followed by UV detection at 200–220 nm. |
| Water Content | Karl Fischer titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Residual Solvents | Gas Chromatography (GC) | Separation and quantification of volatile organic solvents (e.g., methanol, ethanol, acetone) using flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, As, Hg) after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography (IC) | Anion separation and conductivity detection of Cl- and other halides in aqueous solution. |
| Sulfated Ash | Gravimetric analysis | Incineration at 500–600 C followed by weighing of non-volatile inorganic residue. |
| Related Substances | Reverse-phase HPLC | Separation of structurally related impurities (e.g., L-valine, L-valinamide, degradation products) using C18 column and UV detection. |
| pH (1% aqueous solution) | Potentiometric pH measurement | Direct measurement of hydrogen ion activity in a defined aqueous solution using calibrated pH electrode. |
| Appearance | Visual inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Particle Size Distribution | Laser diffraction | Analysis of scattered laser light intensity to determine size distribution of solid particles in suspension. |
| Microbial Contamination | Membrane filtration and colony counting | Quantification of aerobic microorganisms via filtration, membrane transfer to agar media, and incubation followed by colony enumeration. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 230-235°C (decomposes) |
| Optical Rotation | +24.0 to +30.0° (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.