3-Chloro-4-morpholino-1,2,5-thiadiazole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 30165-96-9 |
| Product name | 3-Chloro-4-morpholino-1,2,5-thiadiazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Chloro-4-morpholino-1,2,5-thiadiazole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Chloro-4-morpholino-1,2,5-thiadiazole Supplier from China
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Industrial Applications of 3-Chloro-4-morpholino-1,2,5-thiadiazole
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing fungicides and insecticides | Prepared via nucleophilic substitution of 3-chloro-1,2,5-thiadiazole with morpholine under basic conditions |
| Pharmaceuticals | Structural building block for antiviral or antibacterial agents | Serves as a key intermediate in coupling or cyclization reactions of heterocyclic compounds |
| Chemical Reagents | Sulfur-containing heterocyclic building block for organic synthesis | Acts as an electrophile in substitution reactions with amines and thiols |
Manufacturing Quality Control of 3-Chloro-4-morpholino-1,2,5-thiadiazole
| Test Item | Commonly Used Test Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) Mass Spectrometry (MS) |
Confirm the compound structure by comparing characteristic IR absorption peaks, ¹H NMR chemical shifts and coupling constants, and molecular ion peaks in MS with standard spectra or theoretical values. |
| Assay | High-Performance Liquid Chromatography (HPLC) Gas Chromatography (GC, if applicable) |
Quantitative analysis of the main component content is performed using reversed-phase HPLC (e.g., C18 column) with a UV detector (typically at 210–260 nm wavelength); purity is calculated using external standard method or area normalization method. |
| Related Substances / Impurity Testing | High-Performance Liquid Chromatography (HPLC) | A gradient elution program is used to separate the main peak from potential process-related impurities or degradation products. Reasonable limits of detection (LOD) and quantitation (LOQ) are set, and impurity levels are controlled based on percentage peak area or relative response factor method. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | According to ICH Q3C guidelines, headspace sampling combined with FID detection is used to perform qualitative and quantitative analysis of organic solvents (e.g., dichloromethane, methanol, acetonitrile) used during synthesis. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | The sample is dried at a specified temperature (e.g., 105°C) until constant weight is achieved. The percentage mass loss is calculated to assess moisture and volatile content. |
| Melting Point | Capillary Melting Point Method or Differential Scanning Calorimetry (DSC) | The melting onset and end temperatures are determined using a melting point apparatus or DSC. These values are compared with literature values to evaluate purity and polymorphic consistency. |
| Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | In accordance with ICH Q3D guidelines, trace elemental analysis is performed for potential catalyst residues (e.g., Pd, Ni) to ensure compliance with safety limits. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric KF titration is used to accurately determine the water content, particularly suitable for moisture-sensitive intermediates or active pharmaceutical ingredients (APIs). |
Technical Specifications of 3-Chloro-4-morpholino-1,2,5-thiadiazole
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124-128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Chloro-4-morpholino-1,2,5-thiadiazole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Chloro-4-morpholino-1,2,5-thiadiazole
Safety Information of 3-Chloro-4-morpholino-1,2,5-thiadiazole
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Chloro-4-morpholino-1,2,5-thiadiazole
Industrial 3-Chloro-4-morpholino-1,2,5-thiadiazole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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