China Factory Direct
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| CAS number | 30189-36-7 |
| Product name | N,N'-Di-Boc-L-lysine hydroxysuccinimide ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Lysine side-chain protecting reagent in peptide synthesis | Used selectively to protect the ε-amino group of lysine in solid-phase or solution-phase peptide synthesis, preventing side reactions; the Boc protecting group is subsequently removed via acidolysis (e.g., trifluoroacetic acid) |
| Biochemistry | Protein modification and crosslinking reagent | Conjugates primary amine-containing molecules (e.g., fluorescent probes, biotin) to lysine residues via NHS ester–amine reaction to form stable amide bonds |
| Diagnostics Development | Biomolecule labeling and conjugation | Serves as a linker to covalently attach reporter molecules (e.g., enzymes, dyes) to lysine sites on antibodies or other proteins during immunoassay or molecular probe preparation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound using reversed-phase HPLC with UV detection at 220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by gradient HPLC-UV, using relative response factors or external standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, THF, ethyl acetate) via headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-OES | Quantifies metals (e.g., Fe, Cu, Ni, Pb) after acid digestion by optical emission spectroscopy at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residual Tert-Butyl Alcohol | GC-FID | Detects residual t-BuOH by direct injection GC-FID with internal standard calibration. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using sodium D-line to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Method | Measures mass loss after drying under controlled vacuum and temperature, indicating volatile content and solvent residues. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determines pH of 1% w/v suspension in water using calibrated pH electrode per USP <791>. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution using Mie scattering theory with automated dispersion. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | -25.5±1.5° (c=1, in DMF) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.