Piperazine-2-carboxylic acid dihydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3022-15-9 |
| Product name | Piperazine-2-carboxylic acid dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Piperazine-2-carboxylic acid dihydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Piperazine-2-carboxylic acid dihydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Piperazine-2-carboxylic acid dihydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for synthesizing antiviral agents (e.g., HIV protease inhibitors) and antibacterial drugs | Introduces the piperazine ring structure into multistep organic syntheses via amide bond formation, chiral resolution, or asymmetric synthesis |
| Pharmaceuticals | Side-chain modification in the synthesis of paliperidone, an antipsychotic drug for schizophrenia treatment | Constructs piperazine-2-carboxylic acid dihydrochloride derivatives through esterification, aminolysis, and hydrochloride salt formation |
| Chemicals | Chiral ligand or catalyst precursor for asymmetric catalytic reactions | Forms chiral metal complexes with metals (e.g., Pd, Cu), applied in C–N coupling or cycloaddition reactions |
| Materials | Synthesis of functional polymers containing piperazine moieties (e.g., polyamides, polyureas) | Acts as a diamine monomer in condensation polymerization, imparting flexible chain segments and hydrogen-bonding sites to the polymer |
Manufacturing Quality Control of Piperazine-2-carboxylic acid dihydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Piperazine-2-carboxylic acid dihydrochloride) | Acid-base titration with NaOH | Quantifies total acidic content by neutralizing HCl counterions using standardized sodium hydroxide solution. |
| Water Content | Karl Fischer titration | Measures water via iodine-sulfur dioxide redox reaction in anhydrous methanol medium. |
| Residue on Ignition | Gravimetric analysis | Determines inorganic ash content by high-temperature incineration followed by weighing of residual solids. |
| Heavy Metals | ICP-OES | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) based on element-specific atomic emission intensities. |
| Chloride Impurity | Potentiometric titration with AgNO3 | Detects chloride ions by measuring potential change during silver nitrate titration. |
| Related Substances | HPLC with UV detection | Separates and quantifies structurally similar impurities using reversed-phase chromatography and UV absorbance. |
| Optical Rotation | Polarimetry | Measures specific rotation of chiral compound in solution to confirm enantiomeric identity and purity. |
| pH of Aqueous Solution | pH meter measurement | Determines acidity/basicity of a defined aqueous solution using calibrated pH electrode. |
| Melting Point | Capillary melting point apparatus | Identifies purity and identity by observing temperature range at which solid transitions to liquid. |
| Loss on Drying | Thermogravimetric analysis (TGA) | Quantifies volatile content by measuring mass loss upon controlled heating under inert atmosphere. |
| Sulfated Ash | Gravimetric analysis | Evaluates inorganic residue after sulfuric acid treatment and high-temperature ignition. |
| Microbial Limits | Membrane filtration and colony counting | Assesses aerobic microbial contamination by filtration, culture on agar media, and enumeration of CFUs. |
Technical Specifications of Piperazine-2-carboxylic acid dihydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C (decomposes) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Piperazine-2-carboxylic acid dihydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Piperazine-2-carboxylic acid dihydrochloride
Safety Information of Piperazine-2-carboxylic acid dihydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Piperazine-2-carboxylic acid dihydrochloride
Industrial Piperazine-2-carboxylic acid dihydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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