China Factory Direct
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| CAS number | 302964-08-5 |
| Product name | N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a tyrosine kinase inhibitor for anti-tumor drug development | Used to block cancer cell proliferation signaling pathways by inhibiting kinase activity (e.g., BCR-ABL) |
| Pharmaceuticals | For targeted therapy research in chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST) | Applied as an imatinib analog or derivative in drug synthesis and structural optimization |
| Chemical Research | Used as a tool compound for kinase activity screening | Applied in in vitro enzyme activity assays or cellular experiments to evaluate kinase inhibition efficacy |
| Drug Development | Used as a lead compound for structural modification to improve pharmacokinetic properties | Applied in chemical synthesis to introduce various substituents, optimizing selectivity and bioavailability |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component by retention time and UV absorbance relative to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents by gas chromatographic separation and flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water via coulometric or volumetric titration with iodine-based reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Hg) after acid digestion using mass spectrometry. |
| Chloride Content | Potentiometric Titration | Measures chloride ions using silver nitrate titrant and silver/silver chloride electrode. |
| Sulfated Ash | Gravimetric Analysis | Determines inorganic residue after high-temperature incineration and weighing. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension based on light scattering pattern. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary method. |
| Bulk Density | Tap Density Tester | Measures mass per unit volume of powder after controlled tapping. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of a standardized suspension in purified water. |
| Microbial Contamination | Membrane Filtration | Detects viable aerobic microorganisms by filtration, incubation, and colony enumeration. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 168–172°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.