1-(4-Chlorobenzhydryl)piperazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 303-26-4 |
| Product name | 1-(4-Chlorobenzhydryl)piperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(4-Chlorobenzhydryl)piperazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(4-Chlorobenzhydryl)piperazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(4-Chlorobenzhydryl)piperazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antihistamine drugs, used in the synthesis of second-generation antihistamines such as loratadine | Serves as a key side-chain building block, incorporated into the drug molecule scaffold via N-alkylation or reductive amination |
| Pharmaceuticals | Research tool compound for 5-HT2A receptor antagonism studies | Used in in vitro receptor binding assays and pharmacological activity screening; typically dissolved in DMSO to prepare working solutions |
| Chemicals | Precursor for synthesis of novel functional materials | Participates in metal–organic framework (MOF) ligand design, coordinating transition metal centers through piperazine nitrogen atoms |
Manufacturing Quality Control of 1-(4-Chlorobenzhydryl)piperazine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Chemical Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Utilizes ¹H-NMR and ¹³C-NMR to analyze chemical shifts of hydrogen and carbon atoms in the molecule, confirming structural characteristics of the target compound. |
| Purity Assay | High-Performance Liquid Chromatography (HPLC) | Employs a reversed-phase column and UV detector (e.g., 254 nm); calculates main component purity using peak area normalization or external standard method. |
| Impurity Analysis | HPLC or UPLC-MS | Uses high-resolution chromatography to separate impurity peaks, combined with mass spectrometry (MS) to identify unknown impurities and assess organic impurity levels. |
| Residual Solvent Analysis | Gas Chromatography (GC-FID/HS-GC) | Headspace gas chromatography (HS-GC) with FID detection for quantitative analysis of residual organic solvents such as methanol, ethyl acetate, etc. |
| Loss on Drying | Drying Method (Thermogravimetric Analysis Optional) | Dry sample to constant weight at specified temperature (e.g., 105°C), calculate percentage weight loss to evaluate moisture and volatile content. |
| Sulfated Ash / Residue on Ignition | High-Temperature Ashing Method | Sample is ignited at high temperature (typically 700–800°C); residue of inorganic matter is weighed to assess total inorganic impurities. |
| Heavy Metal Content | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After sample digestion, determines concentrations of elements such as lead, cadmium, mercury, and arsenic by ICP-MS or AAS to meet pharmacopeial limits. |
| Melting Point | Capillary Melting Point Apparatus | Measures initial and final melting temperatures using a digital melting point apparatus to evaluate crystalline purity and physical consistency. |
| pH Value (if in solution form) | pH Meter Measurement | Sample is prepared as an aqueous solution of defined concentration; pH is measured using a calibrated pH meter to assess stability or salt form. |
| Specific Optical Rotation (if chiral) | Polarimeter Measurement | If the molecule contains chiral centers, specific optical rotation is measured at a specified wavelength (e.g., 589 nm) using a polarimeter to evaluate optical purity. |
Technical Specifications of 1-(4-Chlorobenzhydryl)piperazine
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(4-Chlorobenzhydryl)piperazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(4-Chlorobenzhydryl)piperazine
Safety Information of 1-(4-Chlorobenzhydryl)piperazine
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(4-Chlorobenzhydryl)piperazine
Industrial 1-(4-Chlorobenzhydryl)piperazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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