4-Amino-5-chloro-2,1,3-benzothiadiazole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 30536-19-7 |
| Product name | 4-Amino-5-chloro-2,1,3-benzothiadiazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Amino-5-chloro-2,1,3-benzothiadiazole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-5-chloro-2,1,3-benzothiadiazole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-5-chloro-2,1,3-benzothiadiazole
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of gastroenteric drugs (e.g., tegaserod) | Organic synthesis, condensation reactions |
| Pesticides | Intermediate for active ingredients in herbicides or insecticides | Coupling, functional group modification |
| Dyes | Heterocyclic precursor for fluorescent dyes or pigments | Diazotization, coupling reactions |
| Materials Science | Building block for optoelectronic functional materials (e.g., OLEDs or semiconductor polymers) | Polymerization, molecular assembly |
| Analytical Chemistry | Raw material for synthesizing fluorescent probes or bioconjugation reagents | Derivatization, labeling reactions |
Manufacturing Quality Control of 4-Amino-5-chloro-2,1,3-benzothiadiazole
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Main Component Content (Purity) | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase column with mobile phases of methanol/water or acetonitrile/water (containing minor acid or buffer salt), detected by UV detector (typically at 254 nm or 280 nm). Quantification is performed using external standard or internal standard method, accurately determining the main component content and total impurities. |
| Impurity Profiling (Related Impurities) | HPLC-UV / HPLC-MS | Gradient elution HPLC is used to separate potential synthetic intermediates, degradation products, or by-products (e.g., unreacted o-chloroaniline, chlorinated by-products). Impurity structures are identified using UV absorption or mass spectrometry, ensuring compliance with pharmacopoeial or enterprise specifications limits. |
| Moisture Content | Karl Fischer Titration | Based on the quantitative reaction between iodine, sulfur dioxide, pyridine, and methanol with water, moisture is determined via potentiometric or coulometric titration. Suitable for controlling moisture levels in hygroscopic organic compounds (typically ≤0.5%). |
| Chlorine Content | Combustion Ion Chromatography (CIC) or Oxygen Bomb Combustion + Ion Chromatography | Sample is combusted at high temperature in oxygen, converting chlorine into chloride ions, which are quantified by ion chromatography. Used to verify the theoretical chlorine content (theoretical Cl content ~26.8%) and confirm consistency with molecular formula. |
| Melting Point | Melting Point Instrument Measurement | Measured using a digital melting point apparatus. The melting temperature range (literature value ~178–182°C) serves as an initial indicator of purity and crystalline form consistency. |
| Solvent Residuals | Gas Chromatography (GC) | Using headspace injection or direct injection with capillary columns (e.g., DB-624) to separate and detect residual organic solvents (e.g., DMF, ethanol, acetone). Controlled according to ICH Q3C guidelines. |
| UV Absorption Characteristics | UV-Visible Spectrophotometry (UV-Vis) | Sample solution prepared in ethanol or methanol; absorbance spectrum measured in the 200–400 nm range. Characteristic absorption peaks typically appear around 270–290 nm, used for identification and concentration estimation (requires calibration curve). |
| Water Solubility / Dissolution | Shake Flask Method / Visual Observation | Assessed in aqueous solutions at different pH values or common solvents (water, ethanol, acetone, DMSO) to evaluate formulation suitability and purity (impurities often affect solubility). |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion, lead, cadmium, mercury, arsenic, and other heavy metals are quantified, meeting pharmaceutical-grade standards (e.g., Chinese Pharmacopoeia: heavy metals ≤10 ppm). |
| Particle Size Distribution (if solid powder) | Laser Diffraction Particle Size Analysis | Applicable to active pharmaceutical ingredients for formulations; measures D10, D50, D90 particle size parameters to ensure process consistency and dissolution performance. |
| Polymorph Identification | X-Ray Powder Diffraction (XRPD) | Characterized by comparing diffraction peak patterns to confirm crystalline form, preventing stability or dissolution differences caused by polymorphism. |
Technical Specifications of 4-Amino-5-chloro-2,1,3-benzothiadiazole
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to orange crystalline powder |
| Purity | >=99.0% (HPLC) |
| Melting Point | 168–172°C |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Amino-5-chloro-2,1,3-benzothiadiazole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-5-chloro-2,1,3-benzothiadiazole
Safety Information of 4-Amino-5-chloro-2,1,3-benzothiadiazole
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Amino-5-chloro-2,1,3-benzothiadiazole
Industrial 4-Amino-5-chloro-2,1,3-benzothiadiazole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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