Homovanillic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 306-08-1 |
| Product name | Homovanillic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Homovanillic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Homovanillic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Homovanillic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Biomarker for neurological disease diagnosis | Quantitative analysis of urine or cerebrospinal fluid samples by high-performance liquid chromatography (HPLC) or gas chromatography-mass spectrometry (GC-MS), supporting auxiliary diagnosis and research of neurodegenerative disorders such as Parkinson’s disease |
| Pharmaceutical Industry | Pharmacokinetic studies | Used as the primary dopamine metabolite to investigate metabolic pathways, half-life, and bioavailability of dopaminergic drugs |
| Pharmaceutical Industry | Pharmaceutical intermediate | Serves as an organic synthesis building block in molecular modification and synthesis of antioxidant or neuroprotective agents |
| Biochemical Engineering | Lignin degradation research | Used as a model compound to study microbial or enzymatic metabolic pathways and biotransformation mechanisms during lignin degradation |
| Scientific Research | Neurobiochemical research | Applied as an endogenous metabolite reference standard in ex vivo or in vivo experiments to investigate biochemical mechanisms linking oxidative stress and neuronal injury |
| Food Science | Food component analysis | Used as an analytical reference standard to quantify phenolic acid content in fermented or plant-derived foods, supporting assessment of flavor profile and antioxidant activity |
Manufacturing Quality Control of Homovanillic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Homovanillic Acid Content | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with UV or electrochemical detection; mobile phase typically consists of a methanol-buffer salt system (e.g., phosphate buffer) under isocratic elution; suitable for quantitative analysis of HVA in biological samples and pharmaceuticals, offering high sensitivity and excellent separation. |
| Homovanillic Acid Purity | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Quantifies HVA based on its characteristic absorption at specific wavelengths (approximately 280–290 nm); simple and rapid, ideal for preliminary screening, but with lower specificity and susceptible to interference from impurities; commonly used for crude product testing. |
| Structural Confirmation of Homovanillic Acid | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines the separation capability of HPLC with the structural identification power of mass spectrometry; confirms HVA structure via molecular ion peak ([M+H]+ ≈ m/z 181) and fragment ions; suitable for qualitative and quantitative analysis of trace HVA in complex matrices, with high sensitivity and strong specificity. |
| Residual Solvents in Homovanillic Acid | Gas Chromatography (GC) | Used to detect residual organic solvents (e.g., methanol, ethanol) in HVA active pharmaceutical ingredient; employs polar capillary columns with FID detection; sample derivatization may be applied to enhance volatility when necessary. |
| Related Substances of Homovanillic Acid | High-Performance Liquid Chromatography (HPLC) | Utilizes gradient elution to separate HVA from its degradation products or synthesis intermediates (e.g., vanillylmandelic acid, dopamine metabolites); assesses impurity purity and structure by comparing spectral similarity using a diode array detector (DAD). |
| Stability-Indicating Method for Homovanillic Acid | Stability-Indicating HPLC Method | Validated through forced degradation studies (acid, base, oxidation, heat, light) to ensure effective separation of HVA from its degradation products; guarantees that test results accurately reflect true stability, used in formulation quality research and shelf-life determination. |
Technical Specifications of Homovanillic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 162–166°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Homovanillic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Homovanillic acid
Packaging of Homovanillic acid
Industrial Homovanillic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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