China Factory Direct
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| CAS number | 306937-12-2 |
| Product name | Benzoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-4-methoxy- (9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used in the synthesis of biologically active drug molecules, particularly as a key intermediate for constructing structural units containing amino and carboxyl functional groups |
| Pharmaceutical R&D | Peptide and small-molecule drug modification | Employs the BOC protecting group to protect amino groups, enabling selective reactions in multistep syntheses; the BOC group is subsequently removed via acid treatment |
| Fine chemicals | Preparation of functionalized aromatic compounds | Participates in Suzuki coupling, amide condensation, and other reactions to construct functionalized derivatives of complex aromatic systems |
| Materials science | Polymer precursor synthesis | Acts as a monomer or functionalized initiator in polymerization reactions to incorporate methoxy and carboxylic acid functional groups for material property modulation |
| Biochemistry | Probe molecule synthesis | Used to label or conjugate detection tags such as fluorescent probes and biotin, where the BOC group provides reaction orthogonality |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic detection for high sensitivity and specificity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection with anion-exchange column. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using sodium D-line light source in a polarimeter to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition analysis by observing solid-to-liquid phase change range under controlled heating rate. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to derive volume-based particle size distribution. |
| Bulk Density | USP <616> Method I | Measurement of mass per unit volume of powder poured freely into a graduated cylinder without compaction. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142-146°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.