Methyl 5-hydroxynicotinate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 30766-22-4 |
| Product name | Methyl 5-hydroxynicotinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 5-hydroxynicotinate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 5-hydroxynicotinate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 5-hydroxynicotinate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of niacin-based pharmaceuticals and vitamin B3 derivatives, such as nicotinamide and nicotinic acid | Employed as a key intermediate in ester hydrolysis, reduction, and coupling reactions to produce target active pharmaceutical ingredients via multi-step synthesis |
| Agrochemical Intermediates | Used to prepare pyridine-ring-containing agrochemicals with insecticidal and fungicidal activity | Incorporated into agrochemical molecular structures via nucleophilic substitution or cyclization reactions to enhance biological activity and selectivity |
| Organic Synthesis | Serves as a versatile building block for functionalized pyridine-ring derivatives | Participates in cross-coupling reactions—including Suzuki and Heck couplings—or serves as a starting material for hydroxyl group protection and transformation |
Manufacturing Quality Control of Methyl 5-hydroxynicotinate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 260 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities using gradient elution and UV absorbance; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, ethyl acetate) based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent where water reacts stoichiometrically to determine trace moisture content. |
| Heavy Metals | ICP-OES | Multi-element quantification of metallic impurities (e.g., Pb, Cd, Ni) after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by weighing of non-volatile inorganic residue after treatment with sulfuric acid. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing the temperature range over which solid-to-liquid phase change occurs under controlled heating. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength (589 nm). |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of sample against established reference standards under controlled lighting conditions. |
| pH of Aqueous Solution | pH Meter | Electrochemical measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate size distribution of dry powder particles in air dispersion. |
Technical Specifications of Methyl 5-hydroxynicotinate
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 5-hydroxynicotinate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 5-hydroxynicotinate
Packaging of Methyl 5-hydroxynicotinate
Industrial Methyl 5-hydroxynicotinate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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