(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 308242-23-1 |
| Product name | (3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 308242-23-1
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 308242-23-1 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 308242-23-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthetic intermediate for preparing benzodiazepine derivatives, with potential use in central nervous system (CNS) drug development | Critical intermediate in organic synthesis; employed in amidation, coupling, or cyclization reactions to construct the target molecular scaffold |
Manufacturing Quality Control of 308242-23-1
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identity | High-Performance Liquid Chromatography (HPLC), Mass Spectrometry (MS), Nuclear Magnetic Resonance (NMR) | Compare retention time using HPLC; determine molecular ion peak with MS to confirm molecular weight; use NMR (e.g., ¹H-NMR, ¹³C-NMR) to verify structural characteristic peaks and ensure correct compound structure. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC (e.g., C18 column) with ultraviolet detector (UV, typically 254 nm or 220 nm), calculate the area of the main peak by normalization to assess impurity content. |
| Related Substances | HPLC-UV or LC-MS | Gradient elution for separation of possible synthetic intermediates, degradation products, or isomers. Quantify each impurity using reference standards or self-reference method, meeting pharmacopoeia limits. |
| Assay | HPLC external standard method or internal standard method | Establish a standard curve using reference standards of known concentration to determine the content of the main component in the sample, usually calculated as a percentage on a dry basis. |
| Water Content | Karl Fischer Titration | Use Karl Fischer titration to accurately determine the content of bound water and free water in the sample, suitable for compounds sensitive to moisture. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents used during production (e.g., methanol, ethanol, dichloromethane) according to ICH guidelines, using headspace GC-FID analysis. |
| Polymorphism | X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC) | XRD is used to identify different polymorphic forms; DSC measures melting behavior and thermal transitions to determine crystalline state and stability. |
| Optical Purity | Polarimeter | Measure specific rotation at a specific wavelength (e.g., sodium lamp D line, 589 nm) to verify optical purity and configuration consistency of chiral centers. |
| Particle Size Distribution | Laser Diffraction (LDL) | For solid dosage form raw materials, use wet or dry dispersion to measure particle size D10, D50, D90 by laser diffraction, affecting solubility and bioavailability. |
| Heavy Metals and Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detect toxic elements such as lead, cadmium, arsenic, and mercury according to ICH Q3D requirements, ensuring compliance with safety limits. |
Technical Specifications of 308242-23-1
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 218–222°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 308242-23-1
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 308242-23-1
Packaging of 308242-23-1
Industrial 308242-23-1 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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