Boc-N-Methyl-L-phenylglycine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 30925-11-2 |
| Product name | Boc-N-Methyl-L-phenylglycine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Boc-N-Methyl-L-phenylglycine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Boc-N-Methyl-L-phenylglycine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Boc-N-Methyl-L-phenylglycine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for synthesis of peptide-based and small-molecule drugs | Used as an N-α-Boc-protected non-natural amino acid monomer in solid-phase or solution-phase peptide synthesis to form amide bonds |
| Organic Synthesis | Building block for complex molecules containing the N-methylphenylglycine structural motif | Serves as an intermediate in palladium-catalyzed coupling, reductive amination, or alkylation reactions; the Boc group is cleaved under acidic conditions to liberate the free amine |
| Biochemical Research | Structural component of enzyme inhibitors or receptor ligands | Introduced into target molecules via standard peptide coupling methods (e.g., HATU/DIPEA activation) for structure–activity relationship (SAR) studies |
Manufacturing Quality Control of Boc-N-Methyl-L-phenylglycine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210-220 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection, resolving R- and S-enantiomers. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of iodine with water in a pyridine-methanol solvent system. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, ethyl acetate, toluene). |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 500-600 C followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 C using sodium D-line (589 nm), reporting degrees per dm/g/mL. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Boc-glycine, N-methyl-L-phenylglycine) using gradient HPLC. |
| pH of Solution | Potentiometric pH Measurement | Determination of pH in a defined aqueous suspension or solution using a calibrated glass electrode and pH meter. |
Technical Specifications of Boc-N-Methyl-L-phenylglycine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128.0 - 132.0 °C |
| Optical Rotation | +15.0 to +17.0 ° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Boc-N-Methyl-L-phenylglycine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Boc-N-Methyl-L-phenylglycine
Packaging of Boc-N-Methyl-L-phenylglycine
Industrial Boc-N-Methyl-L-phenylglycine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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