(2R,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 309915-46-6 |
| Product name | (2R,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 309915-46-6
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 309915-46-6 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 309915-46-6
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral Drug Intermediates | Used to synthesize piperazine derivatives with defined stereochemistry, serving as core structural building blocks for drug molecules |
| Pharmaceutical Industry | Active Pharmaceutical Ingredient (API) Synthesis | Serves as a key chiral source for piperazine-containing drugs (e.g., antidepressants, antipsychotics, anti-infectives) in API construction |
| Pharmaceutical Industry | Asymmetric Synthesis | Leverages its chiral center to induce stereoselectivity, enabling synthesis of high-enantiopurity drugs and minimizing formation of inactive isomers |
| Organic Synthesis | Chiral Building Blocks | Applied to construct complex organic molecules containing R- or S-configured methyl-substituted piperazine rings |
| R&D Laboratories | Reference Standards / Certified Reference Materials | Used for chiral separation, purity testing, and structural confirmation during pharmaceutical development |
Manufacturing Quality Control of 309915-46-6
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Chemical Purity | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column, with acetonitrile/buffer salt as the mobile phase in gradient elution. The UV detector (e.g., 210 nm) quantifies the purity of the main component and evaluates impurity content. |
| Enantiomeric Purity / Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employs a chiral stationary phase column (e.g., CHIRALPAK® AD-H, OD-H) to separate the (2R,5S) isomer from other enantiomers or diastereomers. Calculates ee (enantiomeric excess) or de (diastereomeric excess) values. |
| Water Content | Karl Fischer Titration (KF Titration) | Determines trace moisture in the sample by coulometric or volumetric method to ensure compliance with standards for loss on drying or water content (typically <0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection, with a DB-624 or similar capillary column for separation. Quantifies residual organic solvents (e.g., methanol, ethyl acetate, DMF) using an FID detector. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirms molecular structure, stereochemistry, and substitution positions using ¹H NMR, ¹³C NMR, and 2D spectra (e.g., COSY, HSQC). |
| Melting Point | Capillary Melting Point Method | Determines the temperature range at which the substance transitions from solid to liquid, serving as a physical constant for identification and purity assessment. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After sample digestion per pharmacopoeia methods, detects residual levels of elements such as lead, arsenic, cadmium, and mercury to ensure compliance with ICH Q3D limits. |
| Loss on Drying | Oven Drying Method | Dries the sample under specified temperature (e.g., 60–80°C) and reduced pressure until constant weight. Calculates the percentage of mass loss to indicate volatile matter content. |
| Appearance and Color | Visual Inspection | Observes whether the sample is a white to off-white crystalline solid or powder, without visible foreign matter or abnormal discoloration. |
| pH Value (if in solution form) | pH Meter Measurement | Prepares a solution of specified concentration in water and measures its acidity or alkalinity using a calibrated pH meter to assess stability or degradation. |
Technical Specifications of 309915-46-6
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -85.9 to -84.3 °C (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 309915-46-6
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 309915-46-6
Packaging of 309915-46-6
Industrial 309915-46-6 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply