China Factory Direct
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| CAS number | 31161-46-3 |
| Product name | 2-BROMO-5-BENZOYLTHIOPHENE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of the antiplatelet drug ticagrelor | Undergoes palladium-catalyzed cross-coupling with amines to construct the thienopyrimidine core structure |
| Organic Synthesis | Used to build novel functional molecules containing brominated thiophene heterocycles | After lithium–halogen exchange, reacts with electrophiles (e.g., aldehydes, ketones, CO₂) or participates in metal-catalyzed coupling reactions such as Suzuki and Heck couplings |
| Materials Science | Building block for organic semiconductor materials in OLEDs and organic field-effect transistors (OFETs) | Introduced into conjugated polymer backbones via Stille or Suzuki coupling to tune HOMO/LUMO energy levels and charge-carrier transport properties |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and visible impurities under natural light or standard illumination. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with UV detection (e.g., 254 nm), quantitatively analyze the target compound by comparing retention time and peak area with those of a reference standard. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Utilize ¹H-NMR and ¹³C-NMR to analyze molecular structure, confirming that the chemical environments of hydrogen and carbon atoms match the expected structure. |
| Molecular Weight Confirmation | Mass Spectrometry (MS) | Determine the molecular ion peak using electrospray ionization (ESI) or electron impact ionization (EI-MS), verifying whether the measured molecular weight matches the theoretical value for C₁₁H₇BrOS (approximately 266.14 g/mol). |
| Solubility | Solubility Test | Add the sample to solvents such as water, ethanol, ethyl acetate, and dichloromethane, shake thoroughly, and observe dissolution behavior to determine the applicable solvent range. |
| Water Content | Karl Fischer Titration | Quantitatively determine moisture content via the reaction between iodine and sulfur dioxide in pyridine and methanol, suitable for trace water analysis. |
| Residual Solvents | Gas Chromatography (GC) | Use a capillary column with a flame ionization detector (FID) to detect residual organic solvents from production processes (e.g., methanol, ethanol, acetone, dichloromethane). |
| Melting Point | Melting Point Determination | Use an automatic or capillary melting point apparatus to heat the sample and record initial and final melting temperatures, used for identification and purity assessment. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measure residual levels of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeial or safety standards. |
| Related Substances (Impurities) | HPLC (Gradient Elution) | Optimize gradient elution conditions to separate the main peak from impurity peaks, detecting synthesis by-products or degradation products to evaluate sample stability and safety. |
| Test Item | Specification |
|---|---|
| Appearance | White to yellow crystalline powder |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 118–122°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.