7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 31169-27-4 |
| Product name | 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for novel insecticides, used in synthesizing thienopyrimidine-based insecticides (e.g., analogues of flupyradifurone) | Constructs the pyrimidine ring side chain via cross-coupling reactions such as Suzuki coupling or Buchwald–Hartwig amination |
| Pharmaceuticals | Intermediate for kinase inhibitor lead compounds, applied in anticancer drug development | Participates in heterocycle construction and functional group transformation, e.g., nucleophilic substitution with amines to introduce pharmacophores |
| Materials Science | Building block for organic semiconductor functional materials, used to prepare thienopyrimidine-based conjugated polymers | Acts as an electron-accepting unit in Stille or Suzuki polymerization to modulate HOMO/LUMO energy levels |
Manufacturing Quality Control of 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify specified organic solvents (e.g., methanol, acetone, DMF) against calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, based on atomic emission intensity at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against sodium chloride calibration standards. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled ashing at 700-800 C; reported as percentage weight loss. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, using calibrated digital apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against defined reference standards. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to derive D10, D50, and D90 values per ISO 13320. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized tapping (e.g., 100 taps per ASTM D1895). |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and untargeted screening of volatile organic impurities using gas chromatography coupled with mass spectrometry for identification and semi-quantitation. |
Technical Specifications of 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 185-189 °C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
Safety Information of 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
Industrial 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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