China Factory Direct
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| CAS number | 31230-17-8 |
| Product name | 3-Amino-5-methylpyrazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of novel fungicidal intermediates | Constructs pyrazole ring structures via acylation and cyclization reactions for preparing broad-spectrum antimicrobial pesticide active ingredients |
| Pharmaceuticals | Synthesis of anticancer and anti-inflammatory drug intermediates | Serves as a heterocyclic scaffold in drug molecule design; specific functional groups are introduced through multistep synthesis to enhance biological activity |
| Polymers | Used as a functional monomer or crosslinker | Participates in polymerization to improve thermal stability and chemical resistance of the resulting materials |
| Dyes and Pigments | Used as a dye intermediate | Generates dye compounds with specific color properties and fastness via azo coupling or condensation reactions |
| Milestone | Common Testing Methods | Method Overview |
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| Purity and Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column, with gradient elution using water-acetonitrile or methanol as the mobile phase, and a UV detector (typically at 254 nm or 280 nm). Quantification is performed using external or internal standard methods, effectively separating impurities from the main component and accurately determining the content. |
| Impurity Profile Analysis | HPLC-MS (Liquid Chromatography-Mass Spectrometry) | Combines HPLC with a mass spectrometer for structural identification of unknown impurities, especially suitable for detecting synthetic intermediates, degradation products, or by-products (such as oxidation products or deamination products), providing molecular weight and fragmentation information. |
| Water Content | Karl Fischer Titration | Utilizes Karl Fischer reagent consisting of iodine, sulfur dioxide, pyridine, and methanol to quantitatively react with water. The water content is determined by potentiometric or coulometric methods, suitable for precise moisture control in organic solid samples (typically ≤ 0.5%). |
| Melting Point | Melting Point Apparatus Method | Measures the melting temperature range using a digital melting point apparatus. It is compared with literature values (approximately 120–125°C) to assess purity and crystallinity. A broad melting range indicates the presence of impurities. |
| UV Absorption Characteristics | UV-Vis Spectrophotometry | Determines characteristic absorption peaks (typically in the range of 260–290 nm) in ethanol or aqueous solution, used for rapid identification and concentration estimation, as well as monitoring changes in absorbance for stability studies. |
| Inorganic Impurities such as Chlorides and Sulfates | Ion Chromatography (IC) or Colorimetric Method | Uses ion chromatography to detect residual halide ions or sulfate ions; or uses classical colorimetric methods (e.g., silver nitrate precipitation for chlorides), ensuring that inorganic impurities meet pharmaceutical or industrial-grade standards (e.g., ≤10 ppm). |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection GC-FID/ECD to detect residual organic solvents (e.g., methanol, ethanol, acetone, DMF) from the synthesis process, controlling their levels according to ICH Q3C guidelines. |
| Crystal Form and Crystalline State | X-ray Powder Diffraction (XRPD) | Used to confirm the crystal structure and consistency of the crystal form, preventing differences in solubility and stability caused by different crystal forms, suitable for raw material quality control. |
| Nitrogen Content (Elemental Analysis) | Elemental Analyzer (CHN Analysis) | Determines the content of C, H, and N elements through high-temperature combustion, comparing it with theoretical values to verify the molecular composition and assist in purity assessment, suitable for verifying synthetic routes. |
| Solubility and pH Value | Solubility Test + pH Meter Measurement | Measures its solubility in water, ethanol, and other solvents to assess formulation suitability. After preparing a saturated solution, the pH value is measured (typically weakly alkaline, pH ≈ 7.5–8.5), used for process control and stability evaluation. |
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.