China Factory Direct
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| CAS number | 31251-41-9 |
| Product name | 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Metabolite of the antidepressant amitriptyline; used in psychiatric disease research | Prepared via in vivo metabolism or chemical synthesis for pharmacological activity assessment and pharmacokinetic studies |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible foreign matter under natural or standard lighting conditions. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) and a UV detector at a specific wavelength (e.g., 254 nm, or based on maximum absorbance) to detect the main peak; calculate purity by normalization or peak area percentage. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze proton (¹H-NMR) and carbon (¹³C-NMR) spectra to confirm molecular structure and substituent positions; 2D-NMR techniques (e.g., HSQC, HMBC) may be used if necessary. |
| Molecular Weight Confirmation | Mass Spectrometry (MS, ESI or EI) | Determine the molecular ion peak using electrospray ionization (ESI) or electron ionization (EI) to confirm the exact molecular weight of the target compound. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual volatile organic solvents from the manufacturing process according to pharmacopoeial methods (e.g., Chinese Pharmacopoeia, USP), commonly using an FID detector. |
| Water Content | Karl Fischer Titration | Measure water content in the sample; available as coulometric method (for trace water) or volumetric method (for higher water content), widely used in raw material quality control. |
| Melting Point | Melting Point Determination (Capillary Method or Automated Melting Point Instrument) | Determine the temperature range at which a compound transitions from solid to liquid, used for identification and purity assessment. |
| Related Substances (Impurities) | HPLC with Gradient Elution | Separate the main component from impurities using an optimized gradient mobile phase to detect degradation products or synthetic by-products; evaluate total impurity levels and individual impurity limits. |
| Polymorphic Form Analysis | X-Ray Powder Diffraction (XRPD) | Determine the crystalline form characteristics of a compound; used for quality control and consistency evaluation of polymorphic substances. |
| Particle Size Distribution | Laser Diffraction (LD) | Analyze particle size of solid samples, particularly important in formulation development for evaluating solubility and bioavailability-related properties. |
| Test Item | Specification |
|---|---|
| Appearance | White to orange to green crystalline powder |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 178–182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.