2-CHLORO-4-FLUOROPHENYLBORONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 313545-72-1 |
| Product name | 2-CHLORO-4-FLUOROPHENYLBORONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-CHLORO-4-FLUOROPHENYLBORONIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-CHLORO-4-FLUOROPHENYLBORONIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-CHLORO-4-FLUOROPHENYLBORONIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Used in Suzuki coupling reactions to construct diaryl structures for synthesizing active pharmaceutical ingredients (APIs) of antibiotics, antifungals, or anticancer agents. |
| Agrochemicals | Agrochemical Intermediates | Serves as an arylboronic acid reagent to synthesize key structural motifs in fluorinated insecticides, herbicides, and fungicides. |
| Organic Synthesis | Synthesis of Fluorinated Aromatic Compounds | Applied in cross-coupling reactions (e.g., Suzuki–Miyaura) to introduce the 2-chloro-4-fluorophenyl group into target molecules for producing advanced organic chemicals. |
| Materials Science | Monomer Synthesis for Functional Materials | Used as an intermediate in synthesizing organic light-emitting materials (OLEDs) or liquid crystal materials, where fluorine incorporation modulates material properties. |
Manufacturing Quality Control of 2-CHLORO-4-FLUOROPHENYLBORONIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., residual starting materials, dehalogenated by-products, protodeboronated analogs) using gradient elution and spectral confirmation (MS) where applicable. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatographic separation with flame ionization detection or mass spectrometric identification, quantifying solvents (e.g., THF, toluene, methanol) against internal/external standards per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Inorganic Residues (Sulfated Ash) | Gravimetric Analysis (Ignition at 600–700 °C) | Combustion of organic matrix followed by sulfuric acid treatment and high-temperature ignition to convert inorganic impurities to stable oxides/salts, weighed as residue. |
| Heavy Metals (Pb, Cd, Hg, As, etc.) | ICP-MS or ICP-OES | Digestion of sample in nitric/hydrogen peroxide mixture followed by multi-element quantification via plasma ionization and mass spectrometry or optical emission. |
| Chloride Ion (Cl⁻) | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on an ion-exchange column and quantitative detection based on electrical conductivity of eluted chloride ions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing the temperature range over which solid-to-liquid phase change occurs under controlled heating rate. |
| Residual Palladium (from Suzuki coupling synthesis) | ICP-MS | High-sensitivity quantification of trace Pd after microwave-assisted acid digestion, exploiting isotopic detection (¹⁰⁵Pd or ¹⁰⁶Pd). |
| Particle Size Distribution | Laser Diffraction | Analysis of light scattering pattern from dispersed particles in liquid medium to determine volumetric particle size distribution (D10, D50, D90). |
Technical Specifications of 2-CHLORO-4-FLUOROPHENYLBORONIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 120–124°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-CHLORO-4-FLUOROPHENYLBORONIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-CHLORO-4-FLUOROPHENYLBORONIC ACID
Safety Information of 2-CHLORO-4-FLUOROPHENYLBORONIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-CHLORO-4-FLUOROPHENYLBORONIC ACID
Industrial 2-CHLORO-4-FLUOROPHENYLBORONIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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