7-CHLORO-4-QUINAZOLINOL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 31374-18-2 |
| Product name | 7-CHLORO-4-QUINAZOLINOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7-CHLORO-4-QUINAZOLINOL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7-CHLORO-4-QUINAZOLINOL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7-CHLORO-4-QUINAZOLINOL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate | Serves as a key intermediate in the synthesis of vasodilator drugs (e.g., fasudil and its derivatives) via nucleophilic substitution at the 4-position to introduce piperazine or related moieties. |
| Pharmaceutical Chemicals | Synthesis of quinazolinone-based pharmaceuticals | Functions as the core scaffold for synthesizing 4-substituted quinazolinone derivatives with antitumor, anti-inflammatory, or antihypertensive activity; typically involves further derivatization at the N-3 position or on the phenyl ring. |
| Organic Synthesis | Chemical reagent | Used to construct quinazolinone compound libraries for high-throughput screening; commonly applied in fundamental heterocyclic chemistry research and structural optimization during drug discovery. |
Manufacturing Quality Control of 7-CHLORO-4-QUINAZOLINOL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, DMF) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and matrix-matched calibration. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized lighting and white background. |
| Loss on Drying | Gravimetric Method | Measurement of mass loss after drying under specified temperature and vacuum conditions, indicating volatile matter content. |
| Residue on Ignition | Sulfated Ash Method | Determination of inorganic residue after high-temperature ignition following sulfuric acid treatment. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dry powder form using light scattering principles and Mie theory. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
Technical Specifications of 7-CHLORO-4-QUINAZOLINOL
| Test Item | Specification |
|---|---|
| Appearance | Pale-brown solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 248–252°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7-CHLORO-4-QUINAZOLINOL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7-CHLORO-4-QUINAZOLINOL
Packaging of 7-CHLORO-4-QUINAZOLINOL
Industrial 7-CHLORO-4-QUINAZOLINOL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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