5-hydroxy-l-tryptophan Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 314062-44-7 |
| Product name | 5-hydroxy-l-tryptophan |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-hydroxy-l-tryptophan
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-hydroxy-l-tryptophan Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-hydroxy-l-tryptophan
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Production of tryptophan derivatives | Used as a precursor in the synthesis of drugs for treating depression and insomnia |
| Healthcare | Nutritional supplement | Applied as a dietary supplement to support sleep quality and alleviate symptoms of anxiety and depression |
| Research Sector | Biological research | Employed in studies on neurotransmitter synthesis, particularly in investigating the biosynthetic pathway of serotonin |
| Cosmetics Industry | Anti-aging | Utilized as an antioxidant in skincare formulations to mitigate oxidative damage and promote skin health |
Manufacturing Quality Control of 5-hydroxy-l-tryptophan
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., tryptophan, 5-HTP isomers, oxidation/degradation products) via gradient HPLC-UV against reference standards or threshold-based reporting. |
| Optical Rotation | [α]D | Measurement of specific optical rotation using a polarimeter at 20 °C with sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, ethanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis of toxic elements (Pb, Cd, As, Hg, Ni) using inductively coupled plasma mass spectrometry after acid digestion. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Residue on Ignition | Gravimetric Analysis | Incineration at 700–800 °C followed by weighing of non-volatile inorganic residue to assess inorganic impurity load. |
| pH (1% aqueous solution) | pH Potentiometry | Measurement using calibrated pH meter with glass electrode in a 1% (w/v) aqueous solution at 25 °C. |
| Microbial Limits | Membrane Filtration / Plate Count | Enumeration of total aerobic microorganisms and detection of specified pathogens (e.g., E. coli, Salmonella) per USP <61> and <62>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to determine D10, D50, D90 values per ISO 13320. |
| Specific Absorption (A1%1cm at 280 nm) | UV-Vis Spectrophotometry | Measurement of absorbance in 0.1 M HCl solution at 280 nm to verify identity and batch-to-batch consistency per pharmacopoeial monographs. |
| Chloride Content | Ion Chromatography (IC) | Quantification of chloride ion using suppressed conductivity detection after anion exchange separation. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample with sulfuric acid followed by weighing of residual sulfate ash to assess inorganic sulfate impurities. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, confirming identity and crystallinity per USP <741>. |
Technical Specifications of 5-hydroxy-l-tryptophan
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 228°C - 232°C |
| Optical Rotation | -12.0° to -14.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-hydroxy-l-tryptophan
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 5-hydroxy-l-tryptophan
Industrial 5-hydroxy-l-tryptophan Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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