China Factory Direct
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| CAS number | 31462-54-1 |
| Product name | 2-Iodopyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a pharmaceutical intermediate in the synthesis of antitumor, antiviral, and kinase inhibitor compounds | Introduced into target molecular scaffolds via nucleophilic substitution or coupling reactions to construct pyrimidine ring structures |
| Organic Synthesis | Employed as an aryl iodide in transition metal-catalyzed cross-coupling reactions, including Suzuki and Heck couplings | Reacted with coupling reagents such as boronic acids or alkenes under palladium or copper catalysis to generate complex aromatic architectures |
| Materials Science | Applied in the synthesis of functional organic materials containing pyrimidine motifs (e.g., OLED materials, ligands) | Utilized in functional group transformations or coordination assembly to construct optoelectronically active molecules or metal complexes |
| Pesticide R&D | Served as a lead compound or intermediate in the development of novel insecticides or fungicides | Structurally modified and biologically screened to optimize the agrochemical activity of pyrimidine derivatives |
| Detection Item | Common Testing Methods | Method Overview |
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| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | Uses reversed-phase columns (e.g., C18), with methanol/water or acetonitrile/water as the mobile phase, and UV detection (typically at 254 nm or 265 nm). Quantification is performed using external standard or internal standard methods. This method effectively separates 2-iodopyrimidine from impurities, offering high sensitivity and good reproducibility. |
| Impurity Analysis | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines the separation capability of HPLC with the qualitative and quantitative advantages of mass spectrometry, enabling identification and quantification of trace impurities (such as unreacted starting materials, by-products, degradation products, etc.). Particularly effective for characterizing structurally similar impurities. |
| Content Determination | Gas Chromatography (GC) | Applicable to volatile 2-iodopyrimidine. Uses capillary columns (e.g., non-polar or medium-polarity columns) and flame ionization detection (FID). Requires derivatization or high-temperature injection, suitable for specific sample matrices. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR are used to confirm the molecular structure of 2-iodopyrimidine. Chemical shifts, coupling constants, and integration areas are analyzed to verify its chemical structure and purity. Considered the gold standard for confirmation testing. |
| Molecular Weight Determination | Mass Spectrometry (MS) | Common ionization techniques include ESI (Electrospray Ionization) or EI (Electron Impact Ionization). Accurately determines the molecular ion peak ([M]⁺), aiding in molecular formula confirmation. Often used in conjunction with LC-MS. |
| Residual Solvent Testing | Gas Chromatography (GC) | Utilizes headspace injection or direct injection, with capillary columns for separating residual organic solvents (e.g., toluene, ethyl acetate, acetone). Detection is performed using FID or MS, meeting ICH Q3A/Q3C requirements. |
| Water Content | Karl Fischer Titration | Used for detecting trace water in 2-iodopyrimidine. Offers high selectivity and accuracy, and is a pharmacopoeia-recommended method for moisture determination. |
| Melting Point Determination | Melting Point Apparatus Method | Measured via differential scanning calorimetry (DSC) or a melting point apparatus. Used to assess purity and crystalline form stability. A broad melting range or lower-than-expected melting point suggests the presence of impurities. |
| Test Item | Specification |
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| Appearance | Brown Solid |
| ldentification(NMR) | Conforms to structure |
| Purity | ≥95.0% |
| Total of impurities | Maximum 1.00 percent |
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| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.