(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 314771-76-1 |
| Product name | (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 314771-76-1
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 314771-76-1 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 314771-76-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antihypertensive drugs | Used in the synthesis of quinazoline-based pharmaceuticals |
| Pesticides | Synthetic intermediate for herbicides | Applied in the design and synthesis of fluorinated heterocyclic pesticide molecules |
| Chemical Manufacturing | Raw material for high-performance or functional materials | Incorporated into target molecules via nucleophilic substitution or redox reactions |
Manufacturing Quality Control of 314771-76-1
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay | HPLC-UV | Quantifies active pharmaceutical ingredient using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a reference standard. |
| Related Substances | HPLC-UV | Separates and quantifies impurities using gradient HPLC-UV; identification and reporting based on threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water content via coulometric or volumetric titration using iodine generation in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Measures elemental impurities (e.g., Pb, Cd, Ni, As) at sub-ppb levels using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Quantifies chloride ion as an inorganic impurity using suppressed conductivity detection after anion exchange separation. |
| Optical Purity | Chiral HPLC | Assesses enantiomeric excess of the (3S)-tetrahydrofuran moiety using chiral stationary phase and UV detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after incineration at 700-800 C and subsequent weighing. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using Mie scattering theory and optical diffraction patterns. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which crystalline material transitions from solid to liquid using calibrated capillary method. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determines surface acidity/basicity by measuring hydrogen ion activity in a defined aqueous suspension using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
Technical Specifications of 314771-76-1
| Test Item | Specification |
|---|---|
| Appearance | Light Yellow To Light Beige Solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | +7.0 to +8.5° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 314771-76-1
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 314771-76-1
Packaging of 314771-76-1
Industrial 314771-76-1 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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