3-CBZ-AMINOPIPERIDINE HCL Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 31648-54-1 |
| Product name | 3-CBZ-AMINOPIPERIDINE HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 3-CBZ-AMINOPIPERIDINE HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-CBZ-AMINOPIPERIDINE HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-CBZ-AMINOPIPERIDINE HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a synthetic intermediate for preparing bioactive piperidine-containing drug molecules, such as anticancer, antiviral, or central nervous system agents | Employed as an amino-protected piperidine derivative in peptide synthesis or heterocycle construction, participating in coupling reactions (e.g., Suzuki, Buchwald–Hartwig); the benzyloxycarbonyl (Cbz) protecting group is removed via hydrogenation or acidolysis to liberate the free amine for subsequent functional group transformations |
| Organic Synthesis | Used as a key building block for constructing complex molecular frameworks, particularly providing a protected piperidinylamine unit in nitrogen-containing heterocycle synthesis | Typically introduced into target molecules via nucleophilic substitution, reductive amination, or transition-metal-catalyzed cross-coupling; the Cbz group offers selective protection of the amino group, suppressing side reactions and enhancing reaction selectivity |
Manufacturing Quality Control of 3-CBZ-AMINOPIPERIDINE HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting of all impurities above threshold per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, Ni) after acid digestion, with detection limits compliant with ICH Q3D. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration from residual HCl salt. |
| Residue on Ignition | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of non-volatile inorganic residue to assess inorganic ash content. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant impurities. |
| pH (1% w/v aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous suspension to verify acidic character from HCl salt. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values relevant for processability. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens per Ph. Eur. 2.6.12. |
Technical Specifications of 3-CBZ-AMINOPIPERIDINE HCL
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 3-CBZ-AMINOPIPERIDINE HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-CBZ-AMINOPIPERIDINE HCL
Packaging of 3-CBZ-AMINOPIPERIDINE HCL
Industrial 3-CBZ-AMINOPIPERIDINE HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply