China Factory Direct
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| CAS number | 317318-97-1 |
| Product name | Thiazole,5-(chloromethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of anticancer drugs (e.g., bosutinib) | Used to construct thiazole ring systems; participates in organic synthesis reactions including Suzuki coupling and nucleophilic substitution |
| Agrochemicals | Potential intermediate for agrochemically active molecules | Used to synthesize trifluoromethylphenyl thiazole compounds for evaluation of insecticidal or fungicidal activity |
| Chemical Research | Organic synthesis building block | Used to construct complex heterocyclic systems; participates in C–C or C–N bond-forming reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Identifies and quantifies impurities by retention time and peak area relative to main peak using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using capillary GC with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (e.g., Pb, Cd, Hg, As) after acid digestion by atomic emission spectroscopy of excited metal ions. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing of the cooled crucible. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube and controlled heating rate. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light and against specified standards. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light caused by chiral centers in solution using sodium D-line light source. |
| Bulk Density | USP <616> Tap Density Method | Determines mass per unit volume of powder after standardized tapping; calculated from weight and tapped volume. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of dry or wet dispersed particles by analyzing angular dependence of scattered laser light intensity. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.