4'-BROMO-3-CHLOROPROPIOPHENONE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 31736-73-9 |
| Product name | 4'-BROMO-3-CHLOROPROPIOPHENONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4'-BROMO-3-CHLOROPROPIOPHENONE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4'-BROMO-3-CHLOROPROPIOPHENONE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4'-BROMO-3-CHLOROPROPIOPHENONE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of the antidepressant paroxetine | Multi-step organic synthesis involving bromination, chlorination, and Friedel–Crafts acylation, followed by reductive amination and cyclization to construct the benzodioxepane core of paroxetine |
| Pesticide Development | Potential structural motif for insecticidal or fungicidal agents | Serves as a halogenated aryl propanone scaffold for structure–activity relationship (SAR) studies; target activity against insect acetylcholinesterase or fungal cell membranes is evaluated at the laboratory scale |
| Organic Synthesis | Multifunctional aryl haloketone building block for cross-coupling and carbon-chain extension | Participates in Heck, Suzuki, or Stille coupling reactions; also undergoes derivatization via Wittig reaction, reduction, or α-halogenation to construct complex molecular frameworks |
Manufacturing Quality Control of 4'-BROMO-3-CHLOROPROPIOPHENONE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., bromination by-products, dehalogenated analogs) using gradient HPLC and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., acetone, toluene, DMF) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies toxic elements (Pb, Cd, Hg, As) after acid digestion by inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity (if applicable) by optical rotation of solution in sodium D-line light (589 nm). |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or phase separation against established reference standards. |
| pH of Aqueous Solution | pH Meter | Measures hydrogen ion activity in saturated aqueous suspension using calibrated glass electrode. |
| Bulk Density | Tap Density Analyzer | Determines mass per unit volume after standardized tapping per USP <616> for powder flow assessment. |
Technical Specifications of 4'-BROMO-3-CHLOROPROPIOPHENONE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4'-BROMO-3-CHLOROPROPIOPHENONE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4'-BROMO-3-CHLOROPROPIOPHENONE
Safety Information of 4'-BROMO-3-CHLOROPROPIOPHENONE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4'-BROMO-3-CHLOROPROPIOPHENONE
Industrial 4'-BROMO-3-CHLOROPROPIOPHENONE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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