China Factory Direct
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| CAS number | 320-47-8 |
| Product name | 4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Used in the synthesis of aromatic active pharmaceutical ingredients (APIs) containing a trifluoromethyl group, introduced as a benzene-ring substituent to enhance metabolic stability or bioavailability. |
| Agrochemicals | Agrochemical Intermediate | Used in the synthesis of high-efficacy, low-toxicity fluorinated insecticides or herbicides, leveraging its distinct electronic effects to improve pesticidal activity. |
| Organic Synthesis | Fluorinating Reagent and Radiotracer Precursor | Leveraging the reactivity of the cyano and nitro groups, employed in nucleophilic substitution reactions to prepare other fluorinated aromatic derivatives or to synthesize fluorinated radiotracers for positron emission tomography (PET). |
| Materials Science | Functional Monomer | Serves as a functional monomer in polymerization reactions or small-molecule modification to produce organic materials with tailored optoelectronic or corrosion-resistant properties. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting of individual impurities above threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection for quantification of common organic solvents (e.g., acetone, methanol, toluene) against calibration standards. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic dilution or external calibration. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard solutions. |
| Sulfate Impurity | Ion Chromatography | Anion exchange separation followed by suppressed conductivity detection; quantified relative to sulfate reference standard. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus; onset and clear point recorded per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against defined reference standards. |
| Loss on Drying | Gravimetric Method | Weight loss measured after drying at 105 C for 2 hours under vacuum; reflects volatile and moisture content. |
| Residue on Ignition | Sulfated Ash Method | Ignition of sample at 600–700 C after sulfuric acid treatment; residual inorganic ash weighed as percentage of original sample. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dispersed dry powder using Mie scattering theory and calibrated optical model. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 102.0–106.0 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.