China Factory Direct
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| CAS number | 320384-09-6 |
| Product name | FMOC-L-CYSTEIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 5KG/bag25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Biopharmaceuticals | Side-chain protecting reagent for cysteine residues in solid-phase peptide synthesis (SPPS) | In Fmoc-based SPPS, serves as a stable, acid- and base-resistant side-chain protecting group for Cys residues; its sodium sulfonate form provides high water solubility and orthogonal deprotection (cleavable under mild conditions such as TFA/water or TFA/TIS/water without inducing disulfide side reactions) |
| Pharmaceutical R&D | Key intermediate for synthesizing therapeutic peptides containing free thiol groups or multiple disulfide bonds (e.g., insulin analogs, GLP-1 receptor agonists) | Enables selective introduction of controlled thiol reactive sites during synthesis, supporting subsequent site-specific disulfide bond formation or thiol-based conjugation modifications (e.g., PEGylation, toxin conjugation) |
| Biochemical Research | Cysteine-specific modification and crosslinking probe preparation for protein structure-function studies | Permits Cys-selective labeling under mild aqueous conditions, suitable for chemical modification processes involving active proteins, enzymes, and antibody conjugates |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 265 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., FMOC-Cys, des-FMOC derivative, oxidation products) using gradient HPLC-UV. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., DMF, methanol, acetonitrile). |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, using inductively coupled plasma optical emission spectroscopy. |
| Sodium Content | Ion Chromatography | Quantitative analysis of Na+ ions using suppressed conductivity detection after separation on an anion-exchange column with cation eluent. |
| pH (1% w/v solution) | pH Meter Measurement | Potentiometric measurement of aqueous solution pH using calibrated glass electrode and buffer standards. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using sodium D-line light source and temperature-controlled cell to confirm chiral integrity. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature and vacuum, indicating volatile content including residual solvents and moisture. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution by measuring angular scattering pattern of laser beam passing through dispersed sample. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic mesophilic bacteria and molds/yeasts via filtration, membrane transfer, and incubation on appropriate agar media. |
| Endotoxin Level | LAL Assay | Quantification of bacterial endotoxins using Limulus amebocyte lysate reagent, based on enzymatic cascade leading to gel formation or color development. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.2% |
| Optical Rotation | -15.0° to -25.0° (c=1, H2O) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.