China Factory Direct
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| CAS number | 3209-72-1 |
| Product name | ETHYL 5-METHYLISOXAZOLE-3-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for sulfonamide drugs (e.g., sulfisoxazole) and antibacterial synergists | Serves as a starting material or key intermediate; the isoxazole ring is introduced via amidolysis, condensation, and related reactions |
| Pharmaceutical Industry | Synthetic raw material for nonsteroidal anti-inflammatory drugs (e.g., isoxicam) | Hydrolyzed to the corresponding carboxylic acid, followed by amidation or condensation with other heterocycles to construct the drug molecule scaffold |
| Agrochemical Industry | Intermediate for fungicides and insecticides | The isoxazole ring undergoes further chemical modification—such as alkylation or acylation—to synthesize active ingredients |
| Organic Synthesis | General building block for isoxazole derivatives | Reduced at the ester group to yield alcohol derivatives, or reacted with hydrazine to produce acyl hydrazide compounds, enabling construction of complex molecules |
| Physicochemical Research | Mechanistic studies of organic reactions | Used as a model compound to investigate ring-opening and rearrangement reactions of the isoxazole system under acidic or basic conditions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using HPLC coupled with diode-array detection, with identification and quantification against qualified impurity standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection for quantitative analysis of volatile organic solvents based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water, measuring endpoint potentiometrically or coulometrically. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis of toxic metals (e.g., Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C with sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal analysis by observing the temperature range over which solid-to-liquid phase transition occurs under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension using a calibrated glass electrode pH meter. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after ignition at 600-650 C, indicating inorganic contaminants or catalyst residues. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.