China Factory Direct
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| CAS number | 321-37-9 |
| Product name | 4'-CHLORO-2,2,2-TRIFLUOROACETOPHENONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of novel trifluoromethyl phenyl ethanone-based herbicides (e.g., intermediate for sodium trifloxysulfuron) | Preparation of corresponding aniline derivatives via diazotization with aqueous ammonia and sodium nitrite, followed by hydrolysis |
| Pharmaceuticals | Structural building block for anti-inflammatory and antitumor agents (e.g., CF3-phenyl ethanone scaffold used in kinase inhibitor design) | Used as starting material in reductive amination, Suzuki coupling, and other reactions to construct aryl side chains containing a trifluoromethyl group |
| Materials Science | Synthetic intermediate for high-performance liquid crystal monomers and organic light-emitting diode (OLED) materials | Introduction of liquid crystal core structures via halogen exchange or boronic esterification, or extension of conjugated systems via Grignard reaction |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or HPLC-UV | Quantification based on peak area comparison against a certified reference standard using gas chromatography with flame ionization detection or high-performance liquid chromatography with UV detection. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration where iodine reacts stoichiometrically with water in a controlled anhydrous medium. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents by gas chromatography with flame ionization detection using calibrated standards. |
| Heavy Metals (as Pb) | AAS (Flame or Graphite Furnace) | Atomic absorption spectroscopy measures absorbance of ground-state atoms in a flame or graphite furnace after acid digestion. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of chloride anions on an ion-exchange column followed by conductivity detection and quantification against calibration standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, observed visually under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference samples under standardized lighting conditions. |
| Loss on Drying (LOD) | Gravimetric Analysis (Thermogravimetry) | Measurement of mass loss after drying under specified temperature and vacuum or air flow conditions. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities using reversed-phase HPLC with UV absorbance detection at appropriate wavelength. |
| Residual Catalyst (e.g., Pd) | ICP-MS | Inductively coupled plasma mass spectrometry detects trace metal catalyst residues after microwave-assisted acid digestion. |
| pH of Aqueous Slurry | pH Meter | Electrochemical measurement of hydrogen ion activity in a defined suspension of the compound in water or water:isopropanol. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine size distribution of dry powder particles. |
| Test Item | Specification |
|---|---|
| Appearance | White or colorless to almost white crystalline solid |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 74.0–77.0°C |
| Total Impurities | <=1.5% (GC-MS) |
| Single Impurity | <=0.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.