5-Methylnicotinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3222-49-9 |
| Product name | 5-Methylnicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Methylnicotinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Methylnicotinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Methylnicotinic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of nicotinic acid derivatives (e.g., intermediate for the lipid-lowering drug acipimox) | Prepared via multi-step organic synthesis, including acylation and reduction, to yield the target drug molecule |
| Pesticides | Intermediate for synthesizing novel herbicides and plant growth regulators | Used as a heterocyclic building block in coupling or cyclization reactions to construct the active molecular scaffold |
| Feed Additives | Nicotinic acid derivative used in animal nutritional supplements | Purified and blended with carriers to formulate premixes, then incorporated into compound feed |
| Chemicals | Organic synthesis intermediate for functional material monomers | Functionalized with polymerizable or optoelectronic groups via esterification, halogenation, Suzuki coupling, and related reactions |
Manufacturing Quality Control of 5-Methylnicotinic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column with water-methanol or buffer solution as the mobile phase, detected by UV detector (approximately 230–260 nm). Quantification is performed using external standard or internal standard method to determine the main component content. Suitable for accurate quantification of high-purity samples. |
| Related Substances / Impurities | High-Performance Liquid Chromatography (HPLC) | Same system as above; gradient elution is used to separate potential synthetic intermediates, isomers, or degradation products. Impurity levels are calculated based on peak areas, typically requiring total impurities to be below 0.5%. |
| Structural Confirmation | Infrared Spectroscopy (IR) | Determines the infrared absorption spectrum of the sample and compares it with reference spectra to confirm the presence of characteristic functional groups (e.g., carboxyl group, aromatic ring, substituted pyridine ring), serving as preliminary structural identification. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ¹³C-NMR analysis of hydrogen and carbon signals, respectively, to confirm the chemical environment of hydrogen and carbon atoms in the molecule—this is considered the authoritative method for structural confirmation. |
| Purity Analysis | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measures absorbance at a specific wavelength (e.g., around 260 nm), combined with molar absorptivity to estimate concentration and purity. Commonly used for rapid screening, but with relatively low specificity. |
| Water Content | Karl Fischer Titration | Based on the reaction between iodine and sulfur dioxide in an anhydrous environment with water. Provides precise measurement of moisture content in samples, suitable for controlling water levels in active pharmaceutical ingredients (typically required ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace injection or direct injection to detect organic solvents (such as methanol, ethanol, acetone, dichloromethane) potentially left over from manufacturing processes, complying with ICH Q3C guidelines. |
| Melting Point | Melting Point Determination Method | Measures the melting temperature using a melting point apparatus or capillary tube method. The typical melting point of 5-methyl nicotinic acid is approximately 178–182°C, used for preliminary identification and purity assessment. |
| Solution Clarity | Visual Turbidity Test | Dissolves the sample in a specified solvent (e.g., water or ethanol) and visually checks whether the solution is clear, used to detect insoluble particles or impurities. |
| Acidity/Alkalinity | pH Measurement Method | Prepares a solution at a defined concentration and measures its pH using a pH meter, assessing the ionization state of the carboxyl group and possible acidic/basic impurities. |
Technical Specifications of 5-Methylnicotinic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Methylnicotinic acid
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NMR Spectra of 5-Methylnicotinic acid
Packaging of 5-Methylnicotinic acid
Industrial 5-Methylnicotinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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