4-Methylnicotinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3222-50-2 |
| Product name | 4-Methylnicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methylnicotinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methylnicotinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methylnicotinic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antitubercular agents (e.g., pyrazinamide analogues) and other nitrogen-containing heterocyclic drugs | Introduced into target molecular structures via esterification, amidation, or coupling reactions |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of biologically active pyridine-based compounds | Active molecules are constructed through nucleophilic substitution, metal-catalyzed coupling, and other organic synthetic steps |
| Chemical Research | Used as an organic building block for the synthesis of functionalized pyridine derivatives | Serves as a ligand precursor in coordination chemistry or in C–H functionalization reactions |
| Materials Science | Potentially used as a ligand component in the preparation of metal–organic frameworks (MOFs) or optoelectronic materials | Forms coordination complexes with metal ions via carboxylic acid groups |
Manufacturing Quality Control of 4-Methylnicotinic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~260 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., 4-methylpyridine, pyridine-3-carboxylic acid) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (Pb, Cd, Hg, As) after acid digestion, with detection at sub-pptr levels. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions derived from potential chlorinated by-products or reagents. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content via iodine generation and stoichiometric reaction with water. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-phase transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of crystallinity and comparison against APHA color standards for yellowish discoloration. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of inorganic ash residue after high-temperature combustion (700–800 °C) in a platinum crucible. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determination of a saturated aqueous suspension (1% w/v) using calibrated glass electrode per USP <791>. |
Technical Specifications of 4-Methylnicotinic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 142-146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methylnicotinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methylnicotinic acid
Packaging of 4-Methylnicotinic acid
Industrial 4-Methylnicotinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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