China Factory Direct
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| CAS number | 32328-03-3 |
| Product name | Diethyl 3-hydroxyglutarate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Chemical Synthesis | Organic synthesis intermediate | Used as an intermediate to construct complex molecular frameworks for the synthesis of pharmaceuticals, natural products, and other fine chemicals |
| Pharmaceuticals | Drug discovery and development | Applied in the synthesis of biologically active compounds for candidate drugs targeting therapeutic areas such as lipid-lowering and anti-inflammatory treatments |
| Fine Chemicals | Functional material precursor | Employed in the preparation of polymers or functionalized materials with specific functional groups, leveraging ester and hydroxyl groups in chemical reactions |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with standard spectra to confirm the presence of characteristic functional groups in 3-hydroxyglutaronic acid diethyl ester, such as ester carbonyl (C=O) and hydroxyl (O-H) groups. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze the chemical shifts, integral areas, and coupling constants of hydrogen atoms using nuclear magnetic resonance technology to verify whether the molecular structure matches the expected structure of 3-hydroxyglutaronic acid diethyl ester. | |
| Content Determination | Gas Chromatography (GC) | Separate the components of the sample using gas chromatography and detect them with a flame ionization detector (FID). Quantify the main component content using external or internal standard methods, suitable for volatile ester compounds. |
| High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column and detect with a UV detector (e.g., near 210 nm). Achieve effective separation and quantification of the main component and impurities under an appropriate mobile phase (e.g., methanol-water or acetonitrile-water system). | |
| Related Substances (Impurities) Check | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic elution procedures to separate and detect potential process impurities and degradation products. Usually control the limit using area normalization or main component self-reference method with correction factors. |
| Moisture | Karl Fischer Titration | Determine moisture content by reacting the sample with Karl Fischer reagent using coulometric or volumetric methods, ensuring the product's dryness meets quality requirements. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Place the sample in a sealed headspace vial and heat it to equilibrium, then inject the gaseous portion into a GC-FID system to detect residual organic solvents used during production (e.g., ethanol, ethyl acetate, etc.). |
| Acid Value / Free Acid | Acid-Base Titration | Determine the free acid in the sample using a standard sodium hydroxide solution, with phenolphthalein as an indicator or potentiometric endpoint detection, to evaluate the degree of ester hydrolysis or residual raw materials. |
| Appearance and Characteristics | Visual Inspection | Observe the color, state (should be a clear, colorless to light yellow liquid), and check for turbidity or foreign matter, serving as an initial quality judgment basis. |
| Test Item | Specification |
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| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.430–1.440 |
| Relative Density (20°C/25°C) | 1.060–1.080 g/cm³ |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.