China Factory Direct
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| CAS number | 32333-53-2 |
| Product name | 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the high-efficacy insecticide flupyradifurone | Forms the critical sulfonamide structure via condensation with nitrogen-containing heterocyclic compounds such as 3-amino-1-methyl-5-pyrazolinone |
| Pharmaceuticals | Sulfonyl chloride precursor for synthesizing anticancer drug candidates and protein kinase inhibitors | Introduces sulfonamide or sulfonate functional groups via ammonolysis or alcoholysis, supporting molecular docking optimization |
| Materials Science | Monomer for high-performance polymers with enhanced thermal and chemical resistance (e.g., sulfonated polyethersulfone modifiers) | Undergoes nucleophilic substitution polycondensation with dihydroxy aromatic monomers (e.g., bisphenol A) to yield trifluoromethyl-containing sulfonated polymer repeat units |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration where iodine reacts stoichiometrically with water in a controlled anhydrous environment. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Separation and quantification of volatile organic solvents using headspace equilibration and GC-FID or GC-MS detection. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities (e.g., sulfonic acids) using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Chloride Ion Impurity | Ion Chromatography (IC) | Separation and quantitative detection of Cl- ions using anion-exchange column and conductivity detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-OES | Multi-element quantification after acid digestion by measuring element-specific atomic emission intensities in high-temperature plasma. |
| Sulfur Content | Combustion IC (Ion Chromatography after Combustion) | Oxidative combustion converts sulfur to sulfate, followed by ion chromatographic separation and conductivity detection. |
| Melting Point | Capillary Melting Point Determination | Thermal transition observed as the temperature range at which solid phase changes to liquid under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards. |
| Bulk Density | ASTM D1895 Method A (Tapped Density) | Measurement of mass per unit volume after mechanical tapping of a known mass in a calibrated cylinder. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to determine size distribution of dry or dispersed particles. |
| Residue on Ignition | Gravimetric Analysis | Mass difference before and after high-temperature ashing to quantify non-volatile inorganic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 72–76°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.