China Factory Direct
|
|
| CAS number | 32384-65-9 |
| Product name | 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing carbohydrate derivatives used in nucleoside-based antiviral drugs | Silyl protection and glycosylation reactions in organic synthesis |
| Organic Synthesis | Chiral synthon for constructing complex carbohydrate structures or chiral molecules | Protecting group chemistry, lactone ring-opening, and functional group transformations |
| Research | Reference standard or reference compound in carbohydrate chemistry research | Chromatographic analysis and spectroscopic characterization (NMR/MS) |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and transparency of the sample. Typically a white to off-white powder or crystalline solid, with no visible impurities. |
| Purity (Active Ingredient Content) | Gas Chromatography (GC) or Gas Chromatography-Mass Spectrometry (GC-MS) | Utilize a DB-5 or similar non-polar capillary column with programmed temperature ramping and a flame ionization detector (FID) or mass spectrometer. Quantify the target compound by comparing retention times and peak areas with reference standards. Suitable for volatile derivatives. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H NMR and ¹³C NMR to identify the compound structure, confirming the position of trimethylsilyl substitution and the lactone ring structure; further verification can be aided by 2D NMR techniques (e.g., HSQC, HMBC). |
| Structure Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Detect characteristic functional group absorption peaks, such as the lactone carbonyl (~1750 cm⁻¹), Si–CH₃ (~1250 cm⁻¹ and ~840 cm⁻¹), etc., to assist in structural confirmation. |
| Water Content | Karl Fischer Titration | Determine water content in the sample; since trimethylsilyl groups are moisture-sensitive, excessive water may cause degradation, thus strict control is required (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Detect possible residual organic solvents (e.g., pyridine, dichloromethane, methanol) in accordance with ICH guidelines, using appropriate chromatographic columns and detectors for quantitative analysis. |
| Melting Point | Melting Point Determination (Capillary Method or DSC) | Determine the melting temperature range as a physical property reference; differential scanning calorimetry (DSC) may also be used for precise measurement. |
| Thermal Stability | Thermogravimetric Analysis (TGA) | Analyze mass changes of the sample during heating to evaluate its thermal decomposition temperature and stability, useful for determining storage conditions. |
| Impurity Analysis | High-Performance Liquid Chromatography (HPLC) or GC | Select an appropriate method based on impurity properties to detect synthetic by-products or degradation products and calculate total impurity content. |
| Silicon Content | Elemental Analysis (EA) or ICP-MS | Determine silicon content via elemental analysis or inductively coupled plasma mass spectrometry (ICP-MS) to verify whether the number of introduced trimethylsilyl groups matches theoretical values. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Optical Rotation | +44.0 to +48.0° (c=1, CHCl3) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.