China Factory Direct
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| CAS number | 3251-69-2 |
| Product name | 4-IMIDAZOLEACETIC ACID HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate synthesis | Used as an organic synthesis intermediate for preparing histamine-related drugs and antiallergic compounds |
| Biochemistry | Buffer and reagent | Applied as a component of buffer systems or in enzymatic reaction studies |
| Fine chemicals | Functional molecule construction | Employed in the construction of nitrogen-containing heterocyclic compounds for synthesizing functional material precursors |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies 4-imidazoleacetic acid hydrochloride by titration with standardized NaOH using phenolphthalein indicator. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying at 105 C under vacuum to determine volatile content including residual solvents and moisture. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based reagent specific for water. |
| Residual Solvents | Gas Chromatography (GC) | Separates and quantifies common organic solvents (e.g., methanol, acetone) using flame ionization detection. |
| Heavy Metals | ICP-OES | Quantifies trace metals (Pb, Cd, Hg, As) by plasma excitation and elemental emission spectroscopy. |
| Chloride Impurity | Potentiometric Titration | Measures chloride ion concentration using silver nitrate titrant and silver/silver chloride electrode. |
| Related Substances | HPLC-UV | Separates and quantifies structurally related impurities using reversed-phase chromatography and UV detection at 210 nm. |
| pH (1% aqueous solution) | pH Potentiometry | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity by measuring rotation of plane-polarized light at 20 C using sodium D-line. |
| Melting Point | Capillary Melting Point Apparatus | Identifies purity and identity by observing temperature range of solid-to-liquid phase transition. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration at 700–800 C. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens per pharmacopeial guidelines. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.