THIODIGLYCOLIC ANHYDRIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3261-87-8 |
| Product name | THIODIGLYCOLIC ANHYDRIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for THIODIGLYCOLIC ANHYDRIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk THIODIGLYCOLIC ANHYDRIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of THIODIGLYCOLIC ANHYDRIDE
| Industry | Application | Process |
|---|---|---|
| Chemical Synthesis | Organic synthesis intermediate for preparing sulfur-containing compounds | Reacted with alcohols or amines to produce thioester or thioamide derivatives |
| Pharmaceuticals | Intermediate for synthesizing active pharmaceutical ingredients (APIs) | Introduces sulfhydryl groups into drug molecules to construct specific functional moieties |
| Polymers & Materials | Used for polymer modification or as a crosslinking agent | Reacts with hydroxyl or amino groups on polymer chains to enhance thermal stability and mechanical properties |
| Agricultural Chemicals | Intermediate for pesticide synthesis | Participates in herbicide or insecticide synthesis pathways to improve biological activity |
| Lubricant Additives | Used to formulate high-performance lubricating oil additives | Reacts with base oils to form sulfur-containing extreme-pressure and anti-wear components |
Manufacturing Quality Control of THIODIGLYCOLIC ANHYDRIDE
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase chromatographic column with aqueous-acetonitrile or methanol as the mobile phase, detected by a UV detector (210–230 nm). Quantification is performed via external or internal standard methods by measuring the peak area of the main component. Suitable for detecting degradation products such as thioglycolic acid and dimers. |
| Water Content | Karl Fischer Titration | Relies on the quantitative reaction between water and the iodine-sulfur dioxide-pyridine-methanol system, measuring trace water content via potentiometric or coulometric methods. Suitable for controlling moisture levels caused by anhydride hydrolysis. |
| Free Thioglycolic Acid | HPLC or Titration (Acid-Base Titration) | HPLC method: Quantified after separation from the main component; Titration method: Titrated with standardized NaOH solution to determine free carboxylic acid groups using phenolphthalein as indicator, calculating free acid content to reflect hydrolysis extent. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, heavy metal ions such as Pb, Cd, Hg, and As are measured using AAS or ICP-MS, conforming to pharmaceutical-grade standards (e.g., ≤10 ppm). |
| Residual Solvents | Gas Chromatography (GC-FID/MS) | Utilizes headspace or direct injection to detect organic solvents potentially residual from production, such as ethanol, acetone, and ethyl acetate, controlled according to ICH Q3C limit guidelines. |
| Appearance and Color | Visual Inspection + Colorimetry (APHA) | Observes the sample as a colorless to pale yellow liquid or low-melting solid; color intensity is measured using a platinum-cobalt colorimeter to control oxidation-induced discoloration. |
| Acid Value (Acidity) | Titration (Alkaline Titration) | Titrated with standardized sodium hydroxide solution to determine free acids (including thioglycolic acid generated by hydrolysis), using phenolphthalein as indicator; results expressed as mg KOH/g to reflect hydrolysis extent. |
| Stability / Degradation Products | HPLC-MS Coupling Technology | Used to identify and quantify degradation products formed under thermal, light, or humid conditions (e.g., dimers, oxidized species), supporting forced degradation studies and shelf-life prediction. |
| Sulfur Content | Oxygen Bomb Combustion + Sulfate Precipitation Titration | The sample is combusted at high temperature to convert sulfur to SO₂, which is absorbed and converted to sulfate. Barium chloride is added to precipitate sulfate, and residual barium is titrated to indirectly calculate total sulfur content, verifying molecular composition. |
| Melting Point / Freezing Point | Capillary Method or Automatic Melting Point Apparatus | Thioglycolic anhydride is a low-melting solid (~25–35°C); melting range determination aids in authenticity verification and assessment of crystalline purity. |
Technical Specifications of THIODIGLYCOLIC ANHYDRIDE
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 62–66°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic sulfurous odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of THIODIGLYCOLIC ANHYDRIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of THIODIGLYCOLIC ANHYDRIDE
Packaging of THIODIGLYCOLIC ANHYDRIDE
Industrial THIODIGLYCOLIC ANHYDRIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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