China Factory Direct
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| CAS number | 327-56-0 |
| Product name | D-Norleucine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug synthesis intermediate for antiviral and anticancer agents | Applied in asymmetric synthesis, chiral resolution, and enzyme-catalyzed transformation |
| Biochemical Research | Amino acid substitution reagent for protein structure and function studies | Applied in solid-phase peptide synthesis (SPPS) and isotopic labeling experiments |
| Food Additives | Nutritional fortifier (L-form is the natural configuration; D-norleucine is rarely used directly and is primarily employed in structure–activity relationship studies) | Not used in mainstream food applications; limited to research-grade functional amino acid evaluation |
| Cosmetics | Building block for novel active ingredients (e.g., antioxidant peptides and penetration-enhancing peptides) | Applied in peptide raw material synthesis and stability modification processes |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (D-Norleucine Content) | HPLC with Chiral Column | Separation and quantification using a chiral stationary phase and UV detection at 200-220 nm. |
| Optical Rotation | [alpha]D | Measurement of specific rotation in aqueous solution using a polarimeter to confirm enantiomeric purity. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Weight loss after drying under specified temperature and time to determine volatile content. |
| Residue on Ignition | Gravimetric (700-800 C) | Mass of inorganic residue remaining after high-temperature ashing of the sample. |
| Heavy Metals (as Pb) | AAS or ICP-OES | Quantification of total heavy metals by atomic absorption or emission spectroscopy after acid digestion. |
| Chloride (Cl-) | Potentiometric Titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode to determine halide content. |
| Sulfate (SO42-) | Turbidimetric Method | Formation and measurement of barium sulfate precipitate in acidic medium. |
| pH (1% w/v aqueous solution) | pH Meter | Electrometric measurement of hydrogen ion activity in a standardized aqueous solution. |
| Related Substances | HPLC with Reverse-Phase Column | Separation and detection of structurally related impurities using UV absorbance. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration based on iodine-sulfur dioxide reaction with water. |
| Microbial Limits | Membrane Filtration or Plate Count | Enumeration of aerobic microorganisms using standardized culture media and incubation. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine size distribution of solid particles. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 267-271°C |
| Optical Rotation | -24.0 to -22.0° (c=1, H2O) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.