China Factory Direct
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| CAS number | 32710-65-9 |
| Product name | 2,6-Dichloroisonicotinonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel pyridine-based insecticides and fungicides | Used as a key intermediate—2,6-dichloro-4-cyanopyridine—to introduce functional groups via nucleophilic substitution, coupling, or hydrolysis reactions, yielding pyridine-ring-containing agrochemical active ingredients |
| Pharmaceuticals | Nitrogen-containing heterocyclic scaffold for antiviral and antitumor drugs | Serves as a precursor for drug molecules featuring cyano-substituted pyridine structures, participating in transition metal-catalyzed reactions such as Suzuki coupling and Buchwald–Hartwig amination |
| Chemicals | Production of high-performance organic pigments and functional materials | Applied in synthesizing cyanopyridine-based optoelectronic materials or dye intermediates, forming conjugated systems through condensation, cyclization, and related reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., acetone, methanol, toluene) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine/methanol solvent system. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion; detection based on element-specific atomic emission intensities in high-temperature plasma. |
| Chloride Impurity (inorganic Cl⁻) | Ion Chromatography (IC) | Separation of anions on anion-exchange column with suppressed conductivity detection; quantifies chloride ion from potential hydrolysis or salt residues. |
| Residual Catalyst (Pd) | ICP-MS | Ultra-trace quantification of palladium after microwave-assisted acid digestion; detection based on mass-to-charge ratio of Pd isotopes. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating of a capillary-packed sample; correlates with crystallinity and purity. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (crystalline solid) and color intensity compared to platinum-cobalt standards. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to determine volumetric particle size distribution in dry or dispersed state. |
| Organic Volatile Impurities (e.g., 2,6-dichloropyridine, 4-chloro-2-cyanopyridine) | GC-MS | Identification and quantification of structurally related impurities using retention time and mass spectral matching against reference standards. |
| Sulfated Ash | Gravimetric Analysis | Combustion at 700–800 °C followed by sulfuric acid treatment and weighing of residual inorganic sulfate ash. |
| Bulk Density | ASTM D1895 | Measurement of mass per unit volume for freely settled and tapped powder samples using standardized graduated cylinder method. |
| Microbial Contamination | Membrane Filtration + Culture | Filtration of dissolved sample through sterile membrane, followed by incubation on nutrient media for aerobic microbial enumeration (if applicable for non-sterile API intermediates). |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.