Labetalol hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 32780-64-6 |
| Product name | Labetalol hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Labetalol hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Labetalol hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Labetalol hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Treatment of hypertension and angina pectoris | Used to block cardiac beta-adrenergic receptors, thereby reducing heart rate, decreasing myocardial contractility, and slowing atrioventricular conduction velocity. |
| Pharmaceuticals | Prophylaxis of migraine | Applied to modulate vascular tone and neurotransmitter release for migraine prophylaxis. |
| Pharmaceutical Research | Use as a beta-adrenergic receptor antagonist in laboratory research | Employed as a pharmacological tool in scientific studies to elucidate the role of beta-adrenergic receptors in cardiovascular function. |
Manufacturing Quality Control of Labetalol hydrochloride
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Observation and Physical Testing | Observe the physical properties of the sample, such as appearance (white or white crystalline powder), solubility, melting point, etc., to ensure they meet the specified requirements. |
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Determine the absorption peaks of the test sample at specific wavelengths (e.g., 210 nm, near 254 nm) and compare with the reference standard spectrum. |
| Infrared Spectroscopy (IR) | Press the sample into a tablet and measure the infrared absorption spectrum, comparing it with the standard spectrum to confirm molecular structural characteristics. | |
| High-Performance Liquid Chromatography (HPLC) Retention Time Comparison | Use HPLC to determine the retention time of the main peak of the sample, and identify it by comparing with that of the reference standard. | |
| Related Substances | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18), gradient or isocratic elution to detect degradation products or synthetic intermediates. Calculate the area of each impurity peak and control the limit. |
| Water Content | Karl Fischer Titration | Accurately determine the moisture content in the sample to avoid the impact of hygroscopy on stability and content determination. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) from the production process using headspace or direct injection methods. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Quantitatively determine the content of the main component (Lorazepam) using external standard method or internal standard method. A C18 column and UV detector (e.g., 210 nm) are commonly used, and the peak area is compared with the reference standard. |
| Solution Clarity and Color | Visual Colorimetry | Dissolve the sample in a certain concentration solution and observe its clarity and color, comparing it with standard turbidity or color solutions as per pharmacopoeia requirements. |
| pH Value | pH Meter Measurement | Dissolve the sample in water or an appropriate solvent and measure the pH value of the solution using a calibrated pH meter, which should be within the specified range. |
| Ignited Residue | Gravimetric Method | Charring the sample at high temperature until constant weight and weighing the residue to control the total amount of inorganic impurities. |
Technical Specifications of Labetalol hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Colorless to almost colorless clear liquid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic, mild |
| Solubility | Freely soluble in methanol, ethanol, and ethyl acetate; slightly soluble in water |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Labetalol hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Labetalol hydrochloride
Packaging of Labetalol hydrochloride
Industrial Labetalol hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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