3,5-Bis(trifluoromethyl)nitrobenzene Bulk Supply for Industrial Use

China Factory Direct
CAS number 328-75-6
Product name 3,5-Bis(trifluoromethyl)nitrobenzene
Stock Stock readily available; annual supply capacity exceeding 1,000 tons.
Grade Pharmaceutical GradeMaterial GradeSpecialty Grade
Packaging 25L/drum200L/drum1000L/IBC
Sample Test Samples Available (Click to Request Samples)
COA View COA
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Supply Type Bulk / Contract manufacturing / OEM
Shipping FCL / LCL available
Payment Terms Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
Manufacturer Greenrock Chemical(China Factory)
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CAS No:328-75-6
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Documents We Provide for 3,5-Bis(trifluoromethyl)nitrobenzene

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart
Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3,5-Bis(trifluoromethyl)nitrobenzene Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of 3,5-Bis(trifluoromethyl)nitrobenzene

Industry Application Process
Pesticides Intermediate for synthesizing novel insecticides and acaricides Reduction to the corresponding aniline derivatives, followed by diazotization and coupling to construct the active molecule
Pharmaceuticals Intermediate for synthesizing anticancer and central nervous system drugs Used as a structural modification unit in multistep organic synthesis; e.g., nitro reduction followed by condensation with acyl chlorides to form amide bonds
Materials Science Building block for liquid crystal monomers and organic optoelectronic materials Selective nitro reduction, nucleophilic substitution of fluorine atoms, or coupling reactions (e.g., Suzuki, Ullmann) to introduce conjugated frameworks

Manufacturing Quality Control of 3,5-Bis(trifluoromethyl)nitrobenzene

Detection Item Common Analytical Method Method Overview
Assay (Purity) Gas Chromatography (GC) with FID detector Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column.
Residual Solvents Headspace Gas Chromatography (HS-GC) Volatile organic impurities are vaporized in sealed vials and quantified by GC-FID or GC-MS against calibration standards.
Water Content Karl Fischer Titration (Coulometric mode) Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically.
Heavy Metals (as Pb) Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) Sample digested in acid matrix; elemental emission intensities measured at characteristic wavelengths and compared to calibration curve.
Chloride Impurity Ion Chromatography (IC) with conductivity detection Anions separated on anion-exchange column; chloride quantified by conductivity response relative to standard solutions.
Nitro Group Content Reduction followed by Acid-Base Titration Nitro groups reduced to aromatic amines with Zn/HCl, then diazotized and titrated with sodium nitrite solution.
Melting Point Capillary Melting Point Apparatus Solid sample heated gradually in capillary tube; temperature range at which solid transitions to liquid is recorded.
Appearance (Color) Visual Inspection against APHA Color Standard Sample dissolved in specified solvent and compared visually to platinum-cobalt standard solutions under controlled lighting.
Acid-Value Potentiometric Titration with NaOH Free acidic impurities titrated with standardized sodium hydroxide solution; endpoint determined by pH inflection point.
Non-Volatile Residue Gravimetric Analysis (Evaporation Method) Sample evaporated to dryness at specified temperature; residue weighed and expressed as mass percent.
Related Substances (Impurity Profile) High Performance Liquid Chromatography (HPLC) with UV detection Separation on reversed-phase C18 column; impurities detected at 254 nm and quantified using external standard method.
Residual Catalyst (Pd) Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Acid-digested sample analyzed for palladium isotopes; detection based on mass-to-charge ratio and signal intensity vs calibration.

Technical Specifications of 3,5-Bis(trifluoromethyl)nitrobenzene

Test Item Specification
Appearance Pale-yellow liquid
Purity >=98.0% (GC-MS)
Total Impurities <=2.0%
Single Impurity <=0.5%
Water Content (KF) <=0.5%
Melting Point 48–52°C
Identification (NMR) Consistent with structure
Identification (IR) Consistent with structure
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of 3,5-Bis(trifluoromethyl)nitrobenzene

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NMR Spectra of 3,5-Bis(trifluoromethyl)nitrobenzene

Safety Information of 3,5-Bis(trifluoromethyl)nitrobenzene

Pictograms
Signal Word Warning
Safety Data Sheet

Packaging of 3,5-Bis(trifluoromethyl)nitrobenzene

We have a diverse range of chemicals in stock. Available in IBC (1000 ltr.), Drums (200 ltr.),Drums (25 ltr.).

Industrial 3,5-Bis(trifluoromethyl)nitrobenzene Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

Industrial
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Factory
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ISO 9001
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Samples
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