China Factory Direct
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| CAS number | 328-75-6 |
| Product name | 3,5-Bis(trifluoromethyl)nitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel insecticides and acaricides | Reduction to the corresponding aniline derivatives, followed by diazotization and coupling to construct the active molecule |
| Pharmaceuticals | Intermediate for synthesizing anticancer and central nervous system drugs | Used as a structural modification unit in multistep organic synthesis; e.g., nitro reduction followed by condensation with acyl chlorides to form amide bonds |
| Materials Science | Building block for liquid crystal monomers and organic optoelectronic materials | Selective nitro reduction, nucleophilic substitution of fluorine atoms, or coupling reactions (e.g., Suzuki, Ullmann) to introduce conjugated frameworks |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic impurities are vaporized in sealed vials and quantified by GC-FID or GC-MS against calibration standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Sample digested in acid matrix; elemental emission intensities measured at characteristic wavelengths and compared to calibration curve. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Anions separated on anion-exchange column; chloride quantified by conductivity response relative to standard solutions. |
| Nitro Group Content | Reduction followed by Acid-Base Titration | Nitro groups reduced to aromatic amines with Zn/HCl, then diazotized and titrated with sodium nitrite solution. |
| Melting Point | Capillary Melting Point Apparatus | Solid sample heated gradually in capillary tube; temperature range at which solid transitions to liquid is recorded. |
| Appearance (Color) | Visual Inspection against APHA Color Standard | Sample dissolved in specified solvent and compared visually to platinum-cobalt standard solutions under controlled lighting. |
| Acid-Value | Potentiometric Titration with NaOH | Free acidic impurities titrated with standardized sodium hydroxide solution; endpoint determined by pH inflection point. |
| Non-Volatile Residue | Gravimetric Analysis (Evaporation Method) | Sample evaporated to dryness at specified temperature; residue weighed and expressed as mass percent. |
| Related Substances (Impurity Profile) | High Performance Liquid Chromatography (HPLC) with UV detection | Separation on reversed-phase C18 column; impurities detected at 254 nm and quantified using external standard method. |
| Residual Catalyst (Pd) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Acid-digested sample analyzed for palladium isotopes; detection based on mass-to-charge ratio and signal intensity vs calibration. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 48–52°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.