China Factory Direct
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| CAS number | 329-98-6 |
| Product name | Phenylmethylsulfonyl fluoride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Organic synthesis intermediate | Used in the preparation of pharmaceutical intermediates for anti-inflammatory drugs and antibiotics |
| Pesticides | Synthesis of insecticides and herbicides | Serves as a key intermediate for sulfonyl fluoride-based pesticides |
| Materials Science | Polymer modification | Applied to introduce sulfonyle groups and enhance material properties |
| Chemical Reagents | Laboratory reagent | Used as a fluorinating agent in organic synthesis reactions |
| Fragrances | Fragrance synthesis | Serves as a synthetic precursor for aromatic compounds |
| Dyes | Dye intermediate | Used in the synthesis of sulfonyle-containing dyes |
| Test Item | Common Testing Methods | Method Overview |
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| Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase column with methanol-water or acetonitrile-water as the mobile phase, and UV detection at 210–220 nm to measure the peak area of PMSF. Quantification is performed using the external standard method, offering high sensitivity and selectivity. |
| Content Determination | Gas Chromatography (GC) | Applicable to PMSF samples with good volatility. Capillary columns are used for separation, and a Flame Ionization Detector (FID) is employed for detection. Thermal stability must be considered; suitable for purity analysis. |
| Moisture Determination | Karl Fischer Titration | Employs an iodine-sulfur dioxide-pyridine-methanol system that reacts quantitatively with water. The endpoint is determined by potentiometric or coulometric titration, enabling accurate measurement of trace moisture in PMSF, meeting pharmacopoeial requirements. |
| Impurity Analysis | HPLC-UV / HPLC-MS | Used to detect degradation products such as benzyl alcohol and sulfonic acid impurities. Gradient elution facilitates separation, while mass spectrometry enables identification of unknown impurities, supporting assessment of product purity and stability. |
| pH Measurement | Glass Electrode Method (pH Meter) | PMSF is dissolved in a suitable amount of anhydrous ethanol or mixed solvent, then the pH is measured using a calibrated pH meter. This assesses the compound’s tendency toward acidic hydrolysis (PMSF is prone to hydrolysis). |
| Melting Point Determination | Capillary Melting Point Method | Dried PMSF sample is loaded into a capillary tube and heated slowly. The melting process is observed; the standard melting point range is approximately 62–65 °C, used for preliminary identification and purity evaluation. |
| Appearance and Color | Visual Inspection | Checks whether the sample appears as a colorless to slightly yellow transparent liquid without suspended particles or precipitates, conforming to pharmaceutical or biochemical reagent appearance standards. |
| Residual Solvent Testing | Gas Chromatography (GC-FID/MS) | Tests for residual organic solvents such as ethanol, acetone, and diethyl ether according to ICH Q3C guidelines. Headspace or direct injection methods are used. |
| Hydrolytic Stability (Indirect) | Titration Method (Alkaline Titration of Hydrolysis Products) | PMSF is hydrolyzed under controlled conditions, and the resulting benzyl alcohol and sulfonic acid products are titrated with standardized NaOH solution. This allows indirect estimation of active ingredient content and evaluates storage stability. |
| Chloride Residue Testing | Ion Chromatography (IC) | Detects possible Cl⁻ contamination from raw materials or synthesis processes. Anion-exchange column coupled with conductivity detection ensures no halogen impurities are present. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 42-46°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.