Boc-His(Trt)-OH Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 32926-43-5 |
| Product name | Boc-His(Trt)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Boc-His(Trt)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Boc-His(Trt)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Boc-His(Trt)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Protective intermediate in peptide synthesis | Used in solid-phase or solution-phase peptide synthesis to simultaneously protect the imidazole ring and amino group of histidine with Boc (tert-butoxycarbonyl) and trityl groups, preventing side reactions and ensuring directional peptide chain assembly |
| Biochemistry | Synthesis of biologically active modified peptides | Employed as a key building block for synthesizing complex peptides—including hormones, enzyme inhibitors, and receptor ligands—enhancing synthetic selectivity and yield |
| Organic Synthesis | Selectively protecting reagent for functional groups | Applied in the synthesis of complex molecules to enable stepwise coupling and functional group modulation via selective deprotection of the Boc or trityl group under acidic conditions |
| Pharmaceutical Manufacturing | Precursor for anticancer and antimicrobial peptides | Utilized in the development of histidine-containing therapeutic peptides, including candidate molecules related to histone deacetylase inhibitors |
Manufacturing Quality Control of Boc-His(Trt)-OH
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and whether caking occurs. Typically appears as a white to off-white powder, free of visible impurities. |
| Identification | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirm compound structure using ¹H NMR and ¹³C NMR by comparing characteristic peak positions with literature or reference spectra. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC (e.g., C18 column) with UV detection (210–254 nm); purity is calculated based on the main peak area (typically ≥98%). |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employ chiral stationary phase columns to detect the presence of D-isomer impurities, ensuring the L-configuration is the major component. |
| Moisture Content | Karl Fischer Titration | Determine total water content (bound and free water) to control moisture's impact on stability (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from synthesis (e.g., dichloromethane, ethyl acetate, DMF), in compliance with ICH limits. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Test for residual heavy metals such as lead, arsenic, mercury, and cadmium to ensure compliance with pharmaceutical or high-purity reagent standards (typically total heavy metals ≤10 ppm). |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the compound, used for auxiliary identification and assessment of crystalline purity. |
| Assay | Titration or HPLC External Standard Method | Quantify the actual content of the active ingredient via acid-base titration or HPLC, commonly used in quality control of active pharmaceutical ingredients or intermediates. |
| Microbial Limits | Microbial Limit Test | If intended for pharmaceutical use, test total bacterial count, molds, yeasts, and specified pathogens (e.g., Escherichia coli) to meet pharmacopoeial requirements. |
Technical Specifications of Boc-His(Trt)-OH
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | +12.5±1.5° (c=1, in DMF) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Boc-His(Trt)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Boc-His(Trt)-OH
Packaging of Boc-His(Trt)-OH
Industrial Boc-His(Trt)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply