5-Methoxy-2-tetralone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 32940-15-1 |
| Product name | 5-Methoxy-2-tetralone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Cosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Methoxy-2-tetralone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Methoxy-2-tetralone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Methoxy-2-tetralone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing anti-inflammatory agents, antihistamines, and selective estrogen receptor modulators (e.g., raloxifene analogues) | Multi-step organic synthesis: target API preparation via O-methylation, Friedel–Crafts acylation, cyclization, and related reactions |
| Fragrances | Fixative and base note component imparting woody and amber notes | Formulated into premium perfumes and soap fragrances; typically incorporated into fragrance formulations at 0.1–0.5 wt% |
Manufacturing Quality Control of 5-Methoxy-2-tetralone
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity and Assay | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with methanol-water or acetonitrile-water as the mobile phase. Detection is performed using a UV detector at 254 nm or 280 nm. Quantification is achieved via external or internal standard methods, enabling effective separation of impurities and accurate determination of the main component with high precision and good reproducibility. |
| Impurity Profile Analysis | High-Performance Liquid Chromatography (HPLC-UV/MS) | Employs HPLC coupled with mass spectrometry (LC-MS) for impurity identification, capable of detecting structurally related impurities (e.g., demethylated products, oxidation products, isomers). Impurity structures are confirmed through mass spectral fragmentation patterns, meeting the impurity control requirements of ICH Q3B. |
| Moisture Content | Karl Fischer Titration | Relies on the quantitative reaction of water with an iodine-sulfur dioxide-pyridine-methanol system. Moisture content in the sample is determined by electrochemical or volumetric titration, suitable for precise measurement of trace water in organic solvents (typically required ≤0.5%). |
| Melting Point | Melting Point Apparatus | The melting point range of the sample is measured using a digital melting point apparatus (literature value approximately 85–89°C). This serves as a preliminary indicator of purity; a narrow melting range (≤2°C) suggests high purity. |
| Residual Solvents | Gas Chromatography (GC-FID/MS) | Headspace or direct injection GC is used with DB-624 or HP-INNOWAX columns to detect residual solvents such as ethanol, acetone, ethyl acetate, and dichloromethane. Limits are controlled according to ICH Q3C guidelines. |
| UV Absorption Characteristics | UV-Visible Spectrophotometry (UV-Vis) | A solution is prepared in ethanol or methanol, and scanned across 200–400 nm to record the maximum absorption wavelength (λmax ≈ 275–285 nm). Used for qualitative identification and rapid concentration estimation (requires calibration curve). |
| Crystal Form and Polymorphism Screening | X-Ray Powder Diffraction (XRPD) | Used to confirm the presence of polymorphism in active pharmaceutical ingredients. Crystal form consistency is assessed by characteristic diffraction peak positions and intensity ratios, ensuring consistent formulation stability and dissolution behavior (applies to solid-state API quality control). |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Sample is digested according to pharmacopeial methods (e.g., USP <231> or EP 2.4.8), followed by determination of heavy metals such as lead, cadmium, arsenic, mercury, and copper. Ensures compliance with international pharmacopeial limits (typically ≤10 ppm). |
| Chloride/Sulfate Impurities | Colorimetric Method (Pharmacopeial Limit Test) | According to general chapters of the Chinese Pharmacopoeia, chloride or sulfate impurities are detected by visual comparison with standard solutions of sodium chloride or potassium sulfate. Suitable for monitoring inorganic salt residues potentially introduced during manufacturing. |
| Volatile Organic Compounds | Headspace Gas Chromatography (HS-GC) | Used for qualitative and quantitative analysis of volatile impurities (e.g., benzene, toluene, tetrahydrofuran). Suitable for monitoring solvent residues during production, offering high sensitivity and ideal for trace-level detection. |
Technical Specifications of 5-Methoxy-2-tetralone
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow liquid to semisolid |
| Purity | ≥98.0% |
| 2-Tetralone | ≤0.5% |
| 1,6-Dimethoxy Naphthalene | ≤0.5% |
| Any other unknown impurirty | ≤1.0% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Methoxy-2-tetralone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Methoxy-2-tetralone
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Industrial 5-Methoxy-2-tetralone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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