H-His(Trt)-OMe · HCl Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 32946-56-8 |
| Product name | H-His(Trt)-OMe · HCl |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for H-His(Trt)-OMe · HCl
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-His(Trt)-OMe · HCl Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-His(Trt)-OMe · HCl
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Raw material for peptide drug synthesis | Serves as a histidine precursor derivative in solid-phase or liquid-phase peptide synthesis, protecting the imidazole group to prevent side reactions. |
| Pharmaceutical Chemicals | Drug intermediate synthesis | Used in synthesizing active pharmaceutical ingredients (APIs) containing histidine motifs, such as anti-ulcer and cardiovascular drugs. |
| Biochemistry | Biochemical reagent | Applied in protein engineering and structural modification and labeling studies of peptide fragments. |
| Chemical Synthesis | Organic synthesis building block | Leverages the stability and selective removal characteristics of the Trt (triphenylmethyl) protecting group to construct complex nitrogen-containing heterocyclic compounds. |
Manufacturing Quality Control of H-His(Trt)-OMe · HCl
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (H-HIS(TRT)-OME.HCl content) | Acid-base titration with standardized NaOH | Quantifies active pharmaceutical ingredient by neutralizing HCl salt with base and detecting endpoint potentiometrically or with indicator. |
| Water content | Karl Fischer titration | Measures water via stoichiometric reaction between water, iodine, sulfur dioxide, and base in anhydrous methanol medium. |
| Residual solvents (e.g., methanol, dichloromethane) | Gas chromatography (GC) with FID | Separates and quantifies volatile organic solvents using capillary column and flame ionization detection. |
| Heavy metals (Pb, Cd, Hg, As) | ICP-MS | Detects trace metal impurities by atomizing and ionizing sample, then measuring elemental mass-to-charge ratios with high sensitivity. |
| Chloride ion (Cl-) | Potentiometric titration with AgNO3 | Determines chloride concentration by precipitation titration using silver nitrate and silver indicator electrode. |
| Related substances (impurities) | Reverse-phase HPLC with UV detection | Separates and quantifies structurally related compounds using C18 column and UV absorbance at 210–220 nm. |
| Optical rotation | [alpha]D measurement using polarimeter | Measures specific rotation of chiral compound in solution to confirm stereochemical integrity and enantiomeric purity. |
| pH of aqueous solution | pH meter measurement | Determines acidity/basicity of 1% w/v aqueous solution using calibrated glass electrode system. |
| Loss on drying (LOD) | Gravimetric analysis after heating at 105 C | Quantifies volatile matter by weight loss after controlled heating under specified time and temperature conditions. |
| Particle size distribution | Laser diffraction | Measures particle size distribution by analyzing angular variation in laser light scattering from dispersed sample. |
| Microbial contamination (Total aerobic count) | Membrane filtration followed by plate count agar incubation | Quantifies viable aerobic microorganisms by filtration, culture on nutrient agar, and colony enumeration after incubation. |
| Residual palladium (if catalytically hydrogenated) | ICP-OES | Quantifies palladium catalyst residue by plasma excitation and emission intensity measurement at characteristic wavelength. |
Technical Specifications of H-His(Trt)-OMe · HCl
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168°C - 172°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0° to -19.0° (c=1, 1M HCl) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of H-His(Trt)-OMe · HCl
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-His(Trt)-OMe · HCl
Packaging of H-His(Trt)-OMe · HCl
Industrial H-His(Trt)-OMe · HCl Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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