China Factory Direct
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| CAS number | 33024-60-1 |
| Product name | 4-Aminotetrahydropyran hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate for synthesizing antibiotics, antiviral agents, and cardiovascular drugs | Introduces the tetrahydropyran ring structure into organic synthesis reactions via nucleophilic substitution or condensation, commonly used to construct nitrogen-containing heterocyclic frameworks |
| Biopharmaceuticals | Protecting group or structural modifier for peptide-based drug synthesis | Functionalizes peptide chains through acylation or alkylation reactions involving its amino group |
| Polymer Materials | Monomer or crosslinker for functionalized polymers | Participates in free-radical or ionic polymerization as an active functional group, enhancing thermal stability and biocompatibility of the resulting materials |
| Pesticide Development | Structural building block for novel pesticide molecules | Constructs biologically active heterocyclic compounds via coupling reactions to improve selective inhibition against target pathogens |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compare the sample's infrared absorption spectrum with a standard reference spectrum to confirm the presence of characteristic functional groups (e.g., N–H, C–O, C–N). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze chemical shifts, coupling constants, and integration areas of hydrogen atoms to verify structural consistency. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column with an appropriate mobile phase (e.g., acetonitrile-buffered aqueous solution) to separate components; quantify the main ingredient using a UV detector. |
| Acid-Base Titration | Exploit its hydrochloride nature by performing non-aqueous or potentiometric titration with a standard alkaline solution (e.g., NaOH) to determine total alkaloid content. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Apply gradient elution to separate and detect process impurities, degradation products, etc., usually quantified by area normalization or with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection with polar or non-polar capillary columns and FID detection to measure residual organic solvents (e.g., methanol, dichloromethane). |
| Water Content | Karl Fischer Titration | Determine water content using volumetric or coulometric methods; suitable for salts containing crystalline water or highly hygroscopic materials. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and measure the weight loss due to volatile substances (including moisture and some solvents). |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using capillary method or digital melting point instrument; serves as an auxiliary indicator of purity and crystal form. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 1% w/v), and measure acidity/basicity using a calibrated pH meter to reflect the dissociation behavior of the hydrochloride salt. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure elemental impurities such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopeial limits. |
| Chloride Content | Ion Chromatography (IC) or Argentometric Method | Determine chloride ion content to verify whether the stoichiometric ratio of the hydrochloride salt matches expectations (theoretical Cl⁻ content approximately 23.5%). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.